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Dolasetron
go.drugbank.com/drugs/DB00757ApprovedInvestigationalDolasetron is an antinauseant and antiemetic agent indicated for the prevention of nausea and vomiting associated with moderately-emetogenic cancer chemotherapy and for the prevention of postoperative … This drug is not shown to have activity at other known serotonin receptors, and has low affinity for dopamine receptors.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33714,L33719] The primary purpose of including naloxone within Suboxone is to act as a deterrent to injection, as injected naloxone would rapidly reverse the effects of buprenorphine. … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.
Synonyms: 1-N-Allyl-14-hydroxynordihydromorphinone, 17-allyl-3,14-dihydroxy-4,5α-epoxymorphinan-6-oneMixtures: OSSICODONE E NALOXONE TEVA, OSSICODONE E NALOXONE TEVAOctamoxin
go.drugbank.com/drugs/DB09249ApprovedWithdrawnThis drug was used in the past as an antidepressant agent in the 1960s, however, has since been discontinued. … Octamoxin, also known as _2-octylhydrazine_, is both an irreversible and nonselective monoamine oxidase enzyme inhibitor (MAOI) of the _hydrazine_ chemical class.
Synonyms: 2-octylhydrazineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeLevorphanol
go.drugbank.com/drugs/DB00854ApprovedA narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Heterocyclic Compounds with 4 or More RingsDL-alpha-Tocopherol
go.drugbank.com/drugs/DB14476ApprovedInvestigationalMixtures: Eden With Vitamins A, C, and E, Folica BECategories: Vitamin EGallamine triethiodide
go.drugbank.com/drugs/DB00483ApprovedWithdrawnA synthetic nondepolarizing blocking drug. … The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac
Synonyms: Trietioduro de galamina, Triéthiodure de GallamineBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
International brands: Cibacen WSMixtures: BENAZEPRIL E IDROCLOROTIAZIDE AUROBINDO, BENAZEPRIL E IDROCLOROTIAZIDE AUROBINDOMagnesium silicate
go.drugbank.com/drugs/DB13249ApprovedWithdrawn[L2603] Under the FDA, magnesium silicate is determined as a member of the substances generally recognized as safe (GRAS) to be used as an anticaking agent.[L2605] … The molecular formula can be expressed more clearly as MgSiO3.xH2O.[T186] It is known as talc and it presents many uses in the cosmetic industry, food industry and pharmaceutical industry.
Diethyltoluamide
go.drugbank.com/drugs/DB11282ApprovedDiethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. … DEET products are largely designed to be applied directly to human skin, where the exact mechanisms of actions in which DEET is capable of repelling insects and causing toxicity to humans is still not
Synonyms: 3-methyl-N,N-diethylbenzamide, N,N-diethyl-m-toluamideInternational brands: m-Delphene