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Regdanvimab
go.drugbank.com/drugs/DB16405ApprovedWithdrawnRegdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. … [A235830,A241995] It received its first full approval in South Korea in September 2021,[A241995] followed by the EU in November 2021.[L39130]
Ceftazidime
go.drugbank.com/drugs/DB00438ApprovedInvestigationalBacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding … [A232920, A232925, A232930] Ceftazidime is a third-generation cephalosporin with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as _Pseudomonas aeruginosa
Mixtures: ZAVİCEFTA 2 G/0.5 G İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 10 ADET, CEFAZIME FOR INJECTION 1 g/vialProducts: Ceftazidim Sandoz 250 mg - Pulver zur Herstellung einer Injektionslösung, Kefazim 500 mg TrockenstechampullePargeverine
go.drugbank.com/drugs/DB15783InvestigationalProducts: SERTAL® 10 MG COMPRIMIDOS RECUBIERTOSCetylpyridinium
go.drugbank.com/drugs/DB11073ApprovedInvestigationalIts salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. … Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties.
Mixtures: GAROL GARGARA, 100 ML, MEBUCAIN 2 MG/1 MG NANELI PASTIL (20 ADET)Categories: Compounds used in a research, industrial, or household settingNalmefene
go.drugbank.com/drugs/DB06230ApprovedInvestigationalWithdrawn[L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. … Nalmefene, a 6-methylene analogue of [naltrexone], is an opioid receptor antagonist.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSulfanilamide
go.drugbank.com/drugs/DB00259ApprovedWithdrawnSulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Avc Cream - 15%Norethindrone enanthate
go.drugbank.com/drugs/DB14678InvestigationalMixtures: MESIGYNA 5 MG+50 MG/1 ML ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTÖR, AI PROFAMILIACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMetronidazole benzoate
go.drugbank.com/drugs/DB15759InvestigationalMixtures: DIARSET NX- M SUSPENSION, METRONIDAZOL BENZOILO/ NIFUROXAZIDA 250MG + 200MG/5 ML SUSPENSIONProducts: AMZOL®250 MG/5 ML SUSPENSIÓN, METRONIDAZOL 250 MG/5 ML SUSPENSIONPacritinib
go.drugbank.com/drugs/DB11697ApprovedInvestigationalof both primary and secondary MF in patients with platelet counts < 50 x 10<sup>9</sup>/L. … [L40793] Approximately 50% of patients with primary MF have a mutation of the _JAK2_ gene, which is also commonly mutated in patients with polycythemia vera or essential thrombocythemia.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesQuinine
go.drugbank.com/drugs/DB00468ApprovedInvestigationalQuinine (GLS-1200) was also investigated in clinical trials for its efficacy in preventing SARS-CoV-2 infection (NCT04408183, terminated) and is planned to be evaluated for preventing sinusitis after endoscopic … It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: QUININE SULPHATE TABLETS 300 mg