Search
Axicabtagene ciloleucel
go.drugbank.com/drugs/DB13915ApprovedInvestigationalAxicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. … [L40054] The development of resulted from early preclinical studies conducted by a group of researchers at the National Cancer Institute (NCI), who demonstrated that T cells expressing an anti-CD19 CAR
Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsSynonyms: Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen receptorAminosalicylic acid
go.drugbank.com/drugs/DB00233ApprovedInvestigationalAn antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Categories: Aminosalicylic Acid and DerivativesProducts: Nemasol Sodium Tab 500mgDyclonine
go.drugbank.com/drugs/DB00645ApprovedInvestigationalDyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Mixtures: Benzethonium Chloride and Dyclonine Hydrochloride, Benzethonium chloride and Dyclonine hydrochlorideSynonyms: 4-n-butoxy-β-(1-piperidyl)propiophenoneANC-501
go.drugbank.com/drugs/DB18907InvestigationalANC-501 is under investigation in clinical trial NCT05439603 (ANC-501 in the Treatment of Adults With Major Depressive Disorder).
Synonyms: 3-(3-Chlorophenyl)-1,5-dihydro-N-(1-methylethyl)-1-[4-[2-(4-morpholinyl)ethyl]phenyl]-5-oxo-4H-1,2,4-triazole-4-acetamideLincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approved[A190621] Clinical use of lincomycin has largely been superseded by its semisynthetic derivative [clindamycin] due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains … in use.
Categories: Macrolides, Lincosamides and StreptograminsProducts: LINCOCIN 600 MG IM/IV AMPUL, 1 ADET, LINCOMYCIN INJECTION 600MG/2MLSensor cyclic diguanylate phosphodiesterase, GAF and GAF domain-containing
go.drugbank.com/bio_entities/BE0004305TargetGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)Polypeptides: Sensor cyclic diguanylate phosphodiesterase, GAF and GAF domain-containingMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
go.drugbank.com/bio_entities/BE0009519TargetHumansMay be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect (PubMed:9001210, PubMed:9268380) … Also involved in Golgi fragmentation (PubMed:9001210, PubMed:9268380).
Polypeptides: Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinaseSignal transducer and activator of transcription 1-alpha/beta
go.drugbank.com/bio_entities/BE0010099TargetHumansInvolved in food tolerance in small intestine: associates with the Gasdermin-D, p13 cleavage product (13 kDa GSDMD) and promotes transcription of CIITA, inducing type 1 regulatory T (Tr1) cells in upper … In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated (PubMed:26479788).
Polypeptides: Signal transducer and activator of transcription 1-alpha/betaAcute naused and vomiting caused by Chemotherapy
go.drugbank.com/conditions/DBCOND0025637Synonyms: Acute Chemotherapy-Induced Nausea and Vomiting, Acute chemotherapy induced nausea and vomitingNon-complicated Skin and Soft Tissue Infections
go.drugbank.com/conditions/DBCOND0046572Drugs: TeicoplaninSynonyms: Non-complicated Skin and Soft Tissue Infections