Dyclonine is an topical anesthetic used prior to examination to suppress the gag reflex or for pain relief from canker sores and fever blisters. Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge.
- Mechanism
- Curator reviewed
Local anesthetics block both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
- Primary indication
- Used to provide topical anesthesia of accessible mucous membranes prior to examination, endoscopy or instrumentation, or other procedures involving the esophagus, larynx, mouth, pharynx or throat, respiratory tract or trachea, urinary tract, or vagina.Curator reviewed · 3 structured indications
- Formula / weight
- C18H27NO2 · 289.4125 g/mol (avg)
- First approval
- Canada, 1997 · United States, 2019
- Also known as
- Dyclocaine
- Brand names
Resolves to
BZEWSEKUUPWQDQ-UHFFFAOYSA-NSMILESCCCCOC1=CC=C(C=C1)C(=O)CCN1CCCCC1What you can answer from here — as of September 23, 2026
Which drugs share a target with Dyclonine, and which of those have an active Phase 3 trial?
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