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Displaying results 1881 - 1890 of 3889 in total
  1. Indication

    Bladder Cancers

    go.drugbank.com/conditions/DBCOND0050427
    Drugs: Ifosfamide · Leucovorin · Methotrexate · Mitomycin · Uracil · Vinblastine
    Synonyms: Malignant neoplasm of bladder, part unspecified
  2. Target

    Proteinase-activated receptor 2

    go.drugbank.com/bio_entities/BE0010726
    TargetHumans

    Can also be transactivated by cleaved F2R/PAR1. … Mediates phosphorylation of nuclear factor NF-kappa-B RELA subunit at 'Ser-536'; the function involves IKBKB and is predominantly independent of G proteins. Involved in cellular migration.

    Synonyms: PAR2, PAR-2
  3. Drug

    Peginterferon alfa-2b

    go.drugbank.com/drugs/DB00022
    ApprovedInvestigational

    Peginterferon alfa-2b is available as a variable dose injectable product (tradename Pegintron) used for the treatment of chronic Hepatitis C. … Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV).

  4. Drug

    Upadacitinib

    go.drugbank.com/drugs/DB15091
    ApprovedInvestigational

    [A189165] Despite a variety of therapeutic agents available for treatment, up to 40% of the patients do not respond to current therapies, including biological therapies. … [A189168] To reduce dose-related toxicity (as seen with some pan-JAK inhibitors) without significantly affecting efficacy, more selective JAK1 inhibitors, upadacitinib and [filgotinib], were developed.

  5. Indication

    Photophobia

    go.drugbank.com/conditions/DBCOND0001062
    Drugs: Diclofenac · Naphazoline
    Synonyms: Does not like light
  6. Drug

    Pinus strobus pollen

    go.drugbank.com/drugs/DB10486
    Approved

    Pinus strobus pollen is the pollen of the Pinus strobus plant. Pinus strobus pollen is mainly used in allergenic testing.

    Mixtures: Treatment Set TS333938, Treatment Set TS128872
  7. Drug

    Bisoctrizole

    go.drugbank.com/drugs/DB11262
    Approved

    Bisoctrizole is not approved by the FDA, but is approved in the EU and other parts of the world as a UV-filter in sunscreens, day care products and skin lightening products at a maximum concentration of

  8. Drug

    Linaclotide

    go.drugbank.com/drugs/DB08890
    ApprovedInvestigational

    [A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013,[L47221] respectively.

  9. Drug

    Melarsomine

    go.drugbank.com/drugs/DB11528
    ExperimentalVet approved

    It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection.

  10. Drug

    Cositecan

    go.drugbank.com/drugs/DB05806
    Investigational

    Cositecan is the novel camptothecin derivative which is also known as Karenitecin. It has been developed for superior oral bioavailability and increased lactone stability. It is used to treat cancer.