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Displaying results 181 - 190 of 145284 in total
  1. Drug

    VOR33

    go.drugbank.com/drugs/DB18624
    Investigational

    VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.

    Synonyms: allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein
  2. Drug

    Fosphenytoin

    go.drugbank.com/drugs/DB01320
    ApprovedInvestigational

    Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.

    Salts: Fosphenytoin sodiumCategories: Phenytoin and Prodrugs, Sodium Channel Blockers
  3. Drug

    TPX-4589

    go.drugbank.com/drugs/DB18604
    Investigational

    TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.

    Synonyms: Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE
  4. Drug

    Phenylbutyric acid

    go.drugbank.com/drugs/DB06819
    ApprovedInvestigational

    It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria fermentation.

    Salts: Sodium phenylbutyrateCategories: sodium phenylbutyrate and ursodoxicoltaurine, sodium phenylbutyrate
  5. Drug

    Sulfacetamide

    go.drugbank.com/drugs/DB00634
    Approved

    An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.

    Salts: Sulfacetamide sodiumMixtures: SODIUM SULFACETAMIDE and SULFUR, Sodium Sulfacetamide and Sulfur
  6. Drug

    Cilastatin

    go.drugbank.com/drugs/DB01597
    ApprovedInvestigational

    Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4.

    Salts: Cilastatin sodiumMixtures: IMIPENEM MONOHYDRATE - CILASTATIN SODIUM, IMIPENEM MONOHYDRATE / CILASTATIN SODIUM
  7. Drug

    Levothyroxine

    go.drugbank.com/drugs/DB00451
    ApprovedInvestigational

    constipation, weight gain, memory impairment, and poor tolerance to cold temperatures. … [F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system.

    Salts: Levothyroxine sodium, Levothyroxine sodium pentahydrateMixtures: Levothyroxine and Liothyronine Thyroid, Levothyroxine and Liothyronine Thyroid
  8. Drug

    Cefoxitin

    go.drugbank.com/drugs/DB01331
    ApprovedInvestigational

    Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.

    Salts: Cefoxitin sodiumProducts: Cefoxitin and Dextrose, Mefoxin Inj 1gm/vial Add-vantag
  9. Drug

    Aminohippuric acid

    go.drugbank.com/drugs/DB00345
    ApprovedInvestigationalWithdrawn

    Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]

    Salts: Aminohippurate sodiumCategories: Indicators and Reagents, Benzamides and benzamide derivatives
  10. Drug

    Fondaparinux

    go.drugbank.com/drugs/DB00569
    ApprovedInvestigational

    angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI); and in the management of ST segment elevation myocardial infarction (STEMI). … Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule.

    Salts: Fondaparinux sodiumCategories: Blood and Blood Forming Organs