DB00345ApprovedInvestigationalWithdrawnSmall molecule
Aminohippuric acid is a hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system. The glycine amide of 4-aminobenzoic acid.
- Mechanism
- Curator reviewed
Aminohippurate is filtered by the renal glomeruli and secreted into the urine by the proximal tubules. By measuring the amount of drug in the urine it is possible to determine functional capacity and effective renal plasma flow.
- Primary indication
- Used to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.Curator reviewed · 1 structured indication
- Formula / weight
- C9H10N2O3 · 194.1873 g/mol (avg)
- First approval
- Canada, 1991 · United States, 1944
- Also known as
- 4-aminohippuric acid · Aminohippurate · N-(p-Aminobenzoyl)glycine · p-aminohippurate · p-aminohippuric acid
Resolves to
Clinical / RWD
Structure
InChIKey
HSMNQINEKMPTIC-UHFFFAOYSA-NSMILESNC1=CC=C(C=C1)C(=O)NCC(O)=OTargets
What you can answer from here — as of September 23, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
11TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Aminohippuric acid, and which of those have an active Phase 3 trial?
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