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Displaying results 181 - 190 of 2517 in total
  1. Drug

    Human immunoglobulin G

    go.drugbank.com/drugs/DB00028
    ApprovedInvestigational

    Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and io...

    Products: INTRAGAM P, BERIGLOBINA - P
  2. Drug

    Dasatinib

    go.drugbank.com/drugs/DB01254
    ApprovedInvestigational

    Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias. … [A11377] Unlike [imatinib], another tyrosine kinase used for the treatment of CML and Ph-positive ALL, dasatinib inhibits the active and inactive conformations of the ABL kinase domain.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  3. Drug

    (1R,2S)-2-Phenylcyclopropanaminium

    go.drugbank.com/drugs/DB02665
    Experimental

    A propylamine formed from the cyclization of the side chain of amphetamine.

  4. Drug

    Penicillium chrysogenum var. chrysogenum

    go.drugbank.com/drugs/DB10439
    Approved

    Penicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  5. Drug

    Sodium bicarbonate

    go.drugbank.com/drugs/DB01390
    ApprovedInvestigational

    Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

  6. Drug

    Liotrix

    go.drugbank.com/drugs/DB01583
    Approved

    It is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in peripheral tissues. … In fact, administration of T3 may result in supratherapeutic levels of T3.

    Categories: P-glycoprotein inducers, Cytochrome P-450 Substrates
  7. Drug

    Relatlimab

    go.drugbank.com/drugs/DB14851
    ApprovedInvestigational

    [L41305] As immune checkpoint inhibitors have limited efficacy when used alone, drugs like relatlimab have been trialed in combination with other checkpoint inhibitors - for example, PD-1 inhibitors like … [A246155] Relatlimab received FDA approval in March 2022, alongside the PD-1 inhibitor [nivolumab] in the combination product Opdualag (Bristol-Myers Squibb), for the treatment of unresectable or metastatic

  8. Drug

    Avelumab

    go.drugbank.com/drugs/DB11945
    ApprovedInvestigational

    Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells.

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
  9. Drug

    Aspergillus repens

    go.drugbank.com/drugs/DB10449
    Approved

    Aspergillus repens is a fungus which can provoke allergic reactions. Aspergillus repens extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  10. Indication

    Obesity

    go.drugbank.com/conditions/DBCOND0015947
    Drugs: Amphetamine · Benzphetamine · Bupropion · Fluoxetine · Lecithin, soybean · Lorcaserin +6 more