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Esomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigational[A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion. … [A177577, A177580] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.
ETC-588
go.drugbank.com/drugs/DB05456ExperimentalLUV are capable of transporting excess cholesterol from the vasculature to the liver for eventual elimination as part of the reverse lipid transport (RLT) pathway. … ETC-588, or LUV (large unilamellar vesicles), is made of naturally occurring lipids that circulate through arteries to facilitate the role of high-density lipoprotein (HDL) in removing accumulated cholesterol
Benzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigationalBenzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products. Benzocaine was first used for l...
Products: Anesgerm LA MUELA Fast Pain ReliefCustirsen
go.drugbank.com/drugs/DB05487InvestigationalCustirsen is a benzopyran with potential antineoplastic activity. Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth a...
Echothiophate
go.drugbank.com/drugs/DB01057ApprovedInvestigationalA potent, long-acting irreversible cholinesterase inhibitor used as an ocular hypertensive in the treatment of glaucoma. Occasionally used for accomodative esotropia.
Aloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalAloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agr...
Mixtures: Lax-ease, C Ottways Lax TabVortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalSMSs were developed because there are many different subtypes of serotonin receptors, however, not all of these receptors appear to be involved in the antidepressant effects of SRIs. … seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional role in the efficacy of SRIs
Xenon Xe-129
go.drugbank.com/drugs/DB17386ApprovedInvestigational[A255178,A255183] The use of hyperpolarized noble gases makes lung MRIs feasible. … Lung MRIs are challenging due to the low proton density of this tissue, as well as the presence of artifacts due to respiration and cardiovascular pulsation movement and air–tissue interfaces.
Homatropine
go.drugbank.com/drugs/DB11181ApprovedHomatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated...