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Displaying results 181 - 190 of 10000 in total
  1. Drug

    Fluvastatin

    go.drugbank.com/drugs/DB01095
    ApprovedInvestigational

    Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. … HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis.

    Products: Fluvastatin Sodium ER, FLUVASTATINA EG
  2. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    [L14180] However, multiple mechanisms may be involved in the anticancer activity of bortezomib.[A204083] Bortezomib was first synthesized in 1995. … [A204083] In May 2003, bortezomib became the first anticancer proteasome inhibitor that was approved by the FDA under the trade name VELCADE.

    Synonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamideProducts: BORTEZOMIB EG, PORIX® 3.5 POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE
  3. Drug

    Guanfacine

    go.drugbank.com/drugs/DB01018
    ApprovedInvestigational

    [L11277] Guanfacine was first described in the literature in 1974.[A189841] Guanfacine was granted FDA approval on 27 October 1986.[L11274] … Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release

    Products: Guanfacine ER, ARİSLOW ER 1 MG UZATILMIŞ SALIMLI TABLET, 7 TABLET
  4. Drug

    5-O-phosphono-alpha-D-ribofuranosyl diphosphate

    go.drugbank.com/drugs/DB01632
    ApprovedWithdrawn

    The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.

    Synonyms: PRib-PP
  5. Drug

    Cholestyramine

    go.drugbank.com/drugs/DB01432
    ApprovedInvestigational

    Cholestyramine resin is quite hydrophilic, but insoluble in water.

    Categories: Compounds used in a research, industrial, or household settingProducts: ANTILIP GRANULADO EN SACHET
  6. Drug

    Vincristine

    go.drugbank.com/drugs/DB00541
    ApprovedInvestigational

    Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea.

    Products: VINCRISTINA EG, VINCRISTINE SULFAT DBL 1 MG/1ML ENJ. SOL. ICEREN FLAKON
  7. Drug

    Venlafaxine

    go.drugbank.com/drugs/DB00285
    ApprovedInvestigational

    [L43030] The immediate formulation of the drug, marketed as Effexor, was first approved by the FDA in 1993 and the extended-release formulation, Effexor XR, was later introduced in 1997. … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI).

    Products: Venlafaxine HCL ER, VENLAFAXINA EG
  8. Drug

    Gadoversetamide

    go.drugbank.com/drugs/DB00538
    Approved

    Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.

    Categories: Compounds used in a research, industrial, or household settingProducts: ENJ. ICIN COZ. ICEREN FLAKON, 10 ML, ENJ. ICIN COZ. ICEREN FLAKON, 15 ML
  9. Target

    Homeobox protein engrailed-2

    go.drugbank.com/bio_entities/BE0004484
    TargetHumans

    Synonyms: Hu-En-2, Homeobox protein en-2
  10. Drug

    Levosulpiride

    go.drugbank.com/drugs/DB16021
    Investigational

    Products: ENDACINE 25 MG SOLUCION EN GOTAS, LEVOSULPIRIDE EG