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Ondansetron
go.drugbank.com/drugs/DB00904ApprovedInvestigationalWithdrawnA competitive serotonin type 3 receptor antagonist. … [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation.
Products: Nu-ondansetron, Nat-ondansetronSodium/potassium-transporting ATPase subunit alpha-1
go.drugbank.com/bio_entities/BE0000732TargetEnzymeTransporterHumansCatalytic subunit of the Na(+)/K(+)-ATPase pump that hydrolyzes ATP to exchange ions across the plasma membrane, exporting 3 Na(+) and importing 2 K(+) per cycle against electrochemical gradients (PubMed … This process maintains essential Na(+) and K(+) gradients for membrane potential and cellular function.
Synonyms: Na(+)/K(+) ATPase alpha-1 subunitV-type sodium ATPase subunit K
go.drugbank.com/bio_entities/BE0001440TargetEnterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)Involved in ATP-driven sodium extrusion.
Synonyms: Na(+)-translocating ATPase subunit KDutasteride
go.drugbank.com/drugs/DB01126ApprovedInvestigationalIt is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. … Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart.
Synonyms: (5α,17β)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamideProducts: Nra-dutasterideLevocarnitine
go.drugbank.com/drugs/DB00583ApprovedInvestigationalConstituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Synonyms: 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner saltProducts: LIPOVITASI NFSucralfate
go.drugbank.com/drugs/DB00364ApprovedInvestigationalSucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis … Sucralfate has been shown to be a well-tolerated and safe drug. It is sold under many brands and is available in both tablet and suspension forms.
Products: Nu-sucralfate - Tab 1gmKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
International brands: Dorixina forte NFProducts: Nu-ketorolac, Nu-ketorolac Ophthalmic SolutionKetoprofen
go.drugbank.com/drugs/DB01009ApprovedInvestigationalVet approvedKetoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Products: GABRILEN N 50MG, GABRILEN N 100MGSodium/potassium-transporting ATPase subunit alpha-4
go.drugbank.com/bio_entities/BE0005031TransporterHumansSperm-specific catalytic alpha subunit of the Na(+)/K(+)-ATPase responsible for ATP-dependent Na(+)/K(+) exchange across the plasma membrane. … Transports 3 Na(+) ions out of the cell and 2 K(+) ions into the cell for each ATP hydrolyze (PubMed:16861705).
Synonyms: Na(+)/K(+) ATPase alpha-4 subunitMedroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigationalMedroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.
Products: Nu-medroxy, Aa-medroxy