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Displaying results 181 - 190 of 10000 in total
  1. Drug

    Secnidazole

    go.drugbank.com/drugs/DB12834
    ApprovedInvestigational

    Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. … It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class

    Synonyms: 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2­ ol, 1-(2­ hydroxypropyl)-2-methyl-5-nitroimidazoleMixtures: ITRACONAZOL 33.3 MG + SECNIDAZOL 166.66 MG CÁPSULA, FLUCONAZOL+SECNIDAZOL 75MG/1000 MG
  2. Drug

    Flubendazole

    go.drugbank.com/drugs/DB08974
    ApprovedInvestigationalWithdrawn

    Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.

    Synonyms: (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester, methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamateCategories: Heterocyclic Compounds, 2-Ring, Antiparasitic Products, Insecticides and Repellents
  3. Drug

    Methylchloroisothiazolinone

    go.drugbank.com/drugs/DB14197
    Approved

    Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. … It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area.

    Synonyms: 4-Isothiazolin-3-one, 5-chloro-2-methyl-, 5-Chloro-N-methylisothiazolin-3-oneCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  4. Drug

    Glyburide

    go.drugbank.com/drugs/DB01016
    ApprovedInvestigational

    [A183617] Glyburide was granted FDA approval on 1 May 1984.[L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120] … [L8123] Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and calcium ion concentrations.

    Synonyms: 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea, 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylureaMixtures: DUPLAX 500 MG/5 MG FILM KAPLI TABLET, 120 ADET, DUPLAX 500 MG/5 MG FILM KAPLI TABLET, 180 ADET
  5. Drug

    Tribromsalan

    go.drugbank.com/drugs/DB20138
    ApprovedWithdrawn

    Tribromsalan is a small molecule drug. Tribromsalan has a monoisotopic molecular weight of 446.81 Da.

    Synonyms: 3,4',5-tribromosalicylanilide
  6. Drug

    Ethotoin

    go.drugbank.com/drugs/DB00754
    Approved

    Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. … The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread of seizure activity rather than to abolish the primary focus of seizure discharges.

    Synonyms: 1-ethyl-2,5-dioxo-4-phenylimidazolidine, (±)-3-ethyl-5-phenylhydantoinCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A Inducers
  7. Drug

    Diflunisal

    go.drugbank.com/drugs/DB00861
    Approved

    Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. … Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of rheumatoid arthritis and osteoarthritis.

    Synonyms: 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid, 5-(2,4-difluorophenyl)salicylic acidCategories: Non COX-2 selective NSAIDS, Salicylic Acid and Derivatives
  8. Drug

    Palbociclib

    go.drugbank.com/drugs/DB09073
    ApprovedInvestigational

    It is a second generation cyclin-dependent kinase inhibitor[A176798] selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. … patients based on findings from postmarketing reports and electronic health records demonstrating safety and clinical efficacy.

    Synonyms: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-8h-pyrido(2,3-d)pyrimidin-7-one, 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-oneMixtures: REAMPLA®, REAMPLA®
  9. Drug

    (9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene

    go.drugbank.com/drugs/DB04187
    Experimental

    Synonyms: (9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene
  10. Drug

    (9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene

    go.drugbank.com/drugs/DB01834
    Experimental

    Synonyms: (9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene