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Voclosporin
go.drugbank.com/drugs/DB11693ApprovedInvestigationalLN is a significant cause of renal failure, morbidity, and death in patients with SLE. … Early and accurate intervention for LN is important in improving clinical outcomes.
Peginterferon alfa-2a
go.drugbank.com/drugs/DB00008ApprovedInvestigationalApproved in 2002 by the FDA, Pegasys is indicated for the treatment of HCV with [DB00811] or other antiviral drugs [FDA Label]. … In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) no longer recommend Peginterferon alfa
Synonyms: PEG-IFN alfa-2ACategories: Compounds used in a research, industrial, or household setting, Interferon Type IRitlecitinib
go.drugbank.com/drugs/DB14924ApprovedInvestigationalIn June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further approved by the EMA in September 2023. … Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family.
Chlorobutanol
go.drugbank.com/drugs/DB11386ApprovedVet approvedWithdrawnSimilar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone. … It also elicits sedative-hypnotic and weak local anesthetic actions in addition to antibacterial and antifungal properties.
Categories: Compounds used in a research, industrial, or household settingLoxoprofen
go.drugbank.com/drugs/DB09212ApprovedInvestigationalIt is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India, and as Oxeno in Argentina. … A transdermal preparation was approved for use in Japan in January 2006.
Perflubutane
go.drugbank.com/drugs/DB12821ApprovedInvestigationalWithdrawnPerflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. … It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress testing; currently the leading procedure for detecting coronary heart disease.
Categories: Compounds used in a research, industrial, or household settingPorfimer sodium
go.drugbank.com/drugs/DB00707ApprovedInvestigationalIt is the first drug to be approved in the use of photodynamic therapy in the United States. … It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent.
International brands: Photofrin IICategories: Sensitizers Used in Photodynamic/radiation TherapyFinotonlimab
go.drugbank.com/drugs/DB18859InvestigationalFinotonlimab is under investigation in clinical trial NCT04560894 (SCT-I10A Plus SCT510 Versus Sorafenib as First-line Therapy for Advanced Hepatocellular Carcinoma).
Ferric sulfate
go.drugbank.com/drugs/DB11171ApprovedIt is used in different fields such as dermatology, dentistry and it is thought to present hemostatic properties by interacting chemically with blood proteins. … [A32355, A32356] By the FDA, ferric sulfate is a direct food substance affirmed in the GRAS category (Generally Recognized As Safe).[L2003]