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Metaxalone
go.drugbank.com/drugs/DB00660ApprovedInvestigationalMetaxalone is associated with few side effects and is available as a 800 mg scored tablet. … It is marketed by King Pharmaceuticals under the brand name Skelaxin®. Its main mechanism of action is thought to involve general central nervous system depression.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingTrimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalTrimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). … In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Mixtures: EMEDUR 200 MG SUPOZITUAR, 5 ADET, EMEDUR 100 MG/20 MG SUPOZİTUAR, 5 ADETSynonyms: N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamideFlumethasone
go.drugbank.com/drugs/DB00663ApprovedVet approvedAs it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. … Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties.
Mixtures: LOCASALENE 0,2MG/G+30MG/G MERHEM, 30 G, LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 15 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPentosan polysulfate
go.drugbank.com/drugs/DB00686ApprovedInvestigationalPentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Synonyms: (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULFATE, (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULPHATEInternational brands: Tavan-SPFlurazepam
go.drugbank.com/drugs/DB00690ApprovedIllicitA benzodiazepine derivative used mainly as a hypnotic.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesPhentolamine
go.drugbank.com/drugs/DB00692ApprovedInvestigationalPhentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. … [L48420, L48415, L48390] Phentolamine is administered intravenously, intramuscularly, submucosally, and topically.
Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-RingSynonyms: 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline, 3-((4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)(4-METHYLPHENYL)AMINO)PHENOLIcodextrin
go.drugbank.com/drugs/DB00702ApprovedInvestigationalIt is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways. … Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers.
Mixtures: EXTRANEAL PERITONEAL DIALYSIS SOLUTION 75 g/l, EXTRANEAL PERITONEAL DIALYSIS SOLUTION 75G/LCategories: Compounds used in a research, industrial, or household settingDelavirdine
go.drugbank.com/drugs/DB00705ApprovedInvestigationalWithdrawnA potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InhibitorsSynonyms: (N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl] methanesulfonamide), 2-(4-(5-methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinaminePorfimer sodium
go.drugbank.com/drugs/DB00707ApprovedInvestigationalIt is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. … It is the first drug to be approved in the use of photodynamic therapy in the United States.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsLamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalIt is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). … A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring.
Mixtures: N/A, N/ACategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring