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Displaying results 1891 - 1900 of 10000 in total
  1. Indication

    Hypochloremic state

    go.drugbank.com/conditions/DBCOND0023348
    Drugs: Ammonium chloride · Sodium chloride
    Synonyms: Other disorders of electrolyte and fluid balance, not elsewhere classified
  2. Target

    Serine/threonine-protein kinase TAO1

    go.drugbank.com/bio_entities/BE0009392
    TargetHumans

    Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules … Phosphorylates MAP2K3, MAP2K6 and MARK2.

    Synonyms: Kinase from chicken homolog B, Thousand and one amino acid protein kinase 1
  3. Indication

    Nonspecific pain

    go.drugbank.com/conditions/DBCOND0099285
    Drugs: Levomenthol
    Synonyms: [D]General aches and pains, Generalised aches and pains
  4. Drug

    Ataluren

    go.drugbank.com/drugs/DB05016
    ApprovedWithdrawn

    This drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any indications. … Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk.

  5. Drug

    Maleic acid

    go.drugbank.com/drugs/DB04299
    Investigational

    Synonyms: cis-but-2-enedioic acid
  6. Drug

    Moxisylyte

    go.drugbank.com/drugs/DB09205
    Approved

    Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist. … [L1172] This drug was developed by the Japanese company Fujirebio and also by the American company Iolab in the late 80s.

    Categories: Genito Urinary System and Sex Hormones
  7. Drug

    Omidubicel

    go.drugbank.com/drugs/DB17132
    ApprovedInvestigational

    Omidubicel is a nicotinamide-modified allogeneic hematopoietic progenitor cell therapy derived from cord blood used as an allogeneic stem cell donor source. … [A258948] A pooled analysis of five prospective clinical trials found that the use of omidubicel led to stable trilineage hematopoiesis, immune competence, and graft durability in extended follow-up

  8. Drug

    Plasminogen

    go.drugbank.com/drugs/DB16701
    ApprovedInvestigational

    [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions to form on the mucous membranes of patients, providing an unmet medical need for patients with … [A236035] This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond the site of injury.

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and Proteins
  9. Drug

    Ferric hydroxide

    go.drugbank.com/drugs/DB13423
    Investigational

    Categories: Blood and Blood Forming OrgansProducts: NOGİSFER 100MG/5 ML ORAL ÇÖZELTİ, 100 ML
  10. Drug

    Tipiracil

    go.drugbank.com/drugs/DB09343
    ApprovedInvestigational

    It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism. … [A31255] TAS-102 is indicated for the treatment of metastatic colorectal cancer which has been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, or with an anti-VEGF

    Mixtures: LONSURF FILM-COATED TABLET 15MG/6.14MG, LONSURF FILM-COATED TABLET 20MG/8.19MG