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Lactitol
go.drugbank.com/drugs/DB12942ApprovedLactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose]. … [A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in chronic idiopathic constipation in February 2020.[L11803]
Categories: Compounds used in a research, industrial, or household settingTechnetium Tc-99m succimer
go.drugbank.com/drugs/DB09436Approved[L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first approved by the FDA on February 23, 2022, under the market name NephroScan.[L40573] … 99m (<sup>99m</sup>Tc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA),[A245643] is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in
Categories: Compounds used in a research, industrial, or household settingStiripentol
go.drugbank.com/drugs/DB09118ApprovedInvestigational[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. … Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.
Trypan blue free acid
go.drugbank.com/drugs/DB09158ApprovedTrypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. … This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Categories: Compounds used in a research, industrial, or household settingIdebenone
go.drugbank.com/drugs/DB09081ApprovedInvestigationalDue to its biochemical mode of action, it's thought that idebenone may re-activate viable-but-inactive retinal ganglion cells (RGCs) in LHON patients [L885]. … Due to its ability to reduce oxidative damage and improve ATP production, idebenone was originally investigated for its potential use in Alzheimer's Disease and other cognitivie disorders [A19769].
Categories: Compounds used in a research, industrial, or household settingOPC-28326
go.drugbank.com/drugs/DB05461ExperimentalAt low doses, OPC 28326 selectively vasodilates the femoral arterial bed due to its inhibitory action at alpha-2-adrenoceptors while having minimal action on systemic blood pressure, heart rate and coronary … It is currently being investigated in the treatment of peripheral vascular diseases and Raynaud's syndrome.
Testosterone undecanoate
go.drugbank.com/drugs/DB13946ApprovedInvestigational[L35970] It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone. … [A246594] There are oral and intramuscular formulations available for testosterone undecanoate: both formulations are indicated for testosterone replacement therapy in adult males with hypogonadism.
Ouabain
go.drugbank.com/drugs/DB01092ApprovedIt is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Categories: Compounds used in a research, industrial, or household settingObeticholic acid
go.drugbank.com/drugs/DB05990ApprovedInvestigationalhepatic decompensation) due to a risk of liver failure, in some cases requiring liver transplantation. … Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation.
Quinidine
go.drugbank.com/drugs/DB00908ApprovedQuinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species. … [A38016] Due to its side effects and increased risk of mortality, the use of quinidine was reduced over the next few decades.
Categories: Compounds used in a research, industrial, or household setting