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Autologous cultured chondrocytes
go.drugbank.com/drugs/DB10997ApprovedInvestigationalAutologous cultured chrondrocytes are used as autologous cell therapy to repair articular cartilage injuries in the knee (femoral condyle) due to acute or repetitive trauma. … The surgical implantation was first performed in Sweden.
mRNA-1010
go.drugbank.com/drugs/DB22484Approvedbenefit to be confirmed in a postmarketing trial. … [L64058] The FDA approved mFLUSIVA on August 5, 2026 for active immunization against influenza in adults 50 years of age and older, making it the first mRNA-based influenza vaccine approved in the United
Factor XIII (human)
go.drugbank.com/drugs/DB12909ApprovedInvestigationalAs the half-life of endogenous Factor XIII is long (5-11 days), prophylactic therapy with the replacement of FXIII can be given every 4-6 to maintain hemostasis[A32363]. … When activated by thrombin at the site of injury, the FXIII pro-enzyme is cleaved resulting in activation of the catalytic A-subunit and dissociation from its carrier B-subunit.
Products: Fibrogammin 1250 IE Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung, Fibrogammin 250 IE Pulver und Lösungsmittel zur Herstellung einer Injektions-/InfusionslösungTestosterone cypionate
go.drugbank.com/drugs/DB13943ApprovedInvestigationalIts benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. … It was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979.
Amphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalWhile Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. … The antibiotic is without effect on bacteria, rickettsiae, and viruses.
Gliclazide
go.drugbank.com/drugs/DB01120ApprovedInvestigational[T238, T360] Gliclazide belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. … a sulfonamide group able to release a proton and the presence of one aromatic group.
Donanemab
go.drugbank.com/drugs/DB16647ApprovedInvestigationalcontribute to the pathophysiology of Alzheimer's Disease (AD). … [L50988] It works to reduce amyloid beta plaques and impede the progression of AD.[L50988]
Drometrizole trisiloxane
go.drugbank.com/drugs/DB11585ApprovedDespite being used elsewhere in the world with relatively few reports of adverse reactions, the FDA continues to cite that the existing scientific record is not sufficient to establish the compound as … The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia
Melatonin
go.drugbank.com/drugs/DB01065ApprovedInvestigationalNutraceuticalVet approvedThe pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus … The secretion of melatonin increases in darkness and decreases during exposure to light, thereby regulating the circadian rhythms of several biological functions, including the sleep-wake cycle.
International brands: Mela-TAgkistrodon piscivorus antivenin
go.drugbank.com/drugs/DB13894ApprovedThe cottonmouth habitat range extends from southeastern Virginia (near the junction of the Appomattox and James rivers) to southern Florida, west to central Texas, Oklahoma, Arkansas, Missouri, and southeastern … In North America, members of the family Crotalidae belong to three genera: the rattlesnakes (Crotalus and Sistrurus spp.) and the copperheads and cottonmouth water moccasins (Agkistrodon spp.)