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Reteplase
go.drugbank.com/drugs/DB00015ApprovedInvestigationalWithdrawnRetavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA.
Synonyms: Human t-PA (residues 1-3 and 176-527)Products: RAPILYSIN 10 U IV ENJ. ICIN STERIL LIYOFILIZE TOZ ICEREN FLAKON, 2 ADETCarboprost tromethamine
go.drugbank.com/drugs/DB00429ApprovedInvestigationalA nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.
Synonyms: 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium (5Z,9α,11β,13E,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oateProducts: HEMABATE INJECTION 250 mcg/ml, HEMABATE STERILE SOLUTION 250MCG/MLBemiparin
go.drugbank.com/drugs/DB09258ApprovedInvestigationalWithdrawnBemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). … Interestingly, current research is underway for the potential benefit of bemiparin in the treatment of tumors and diabetic foot ulcers [L1468, A7866].
Products: HIBOR 2500 IU/0,2 ML KULLANIMA HAZIR 10 ENJEKTOR, HIBOR 3500 IU/0,2 ML SC KULLANIMA HAZIR ENJEKTÖR, 10 ADETIotrolan
go.drugbank.com/drugs/DB09487ApprovedWithdrawnNonionic, isotonic contrast medium designed for intrathecal use.
Categories: Compounds used in a research, industrial, or household settingInternational brands: Osmovist 190, Osmovist 240Telaprevir
go.drugbank.com/drugs/DB05521ApprovedWithdrawnSubtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. … Approved in May 2011 by the FDA, Incivek was indicated for the treatment of HCV genotype 1 in combination with [DB00811], [DB00008], and [DB00022] [FDA Label].
Synonyms: (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydrocyclopenta(c)pyrrole-1-carboxamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsGallium citrate Ga-67
go.drugbank.com/drugs/DB06784ApprovedAlthough the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation
Products: MON.GALYUM-67 74 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET (5 ML), MON.GALYUM-67 74 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET (2.5 ML)Influenza A virus A/Singapore/INFIMH-16-0019/2016 NIB-104 (H3N2) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB14558ApprovedWithdrawnThis defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. … re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it
Synonyms: Influenza A virus A/Singapore/INFIMH-16-0019/2016 NIB-104 (H3N2) antigen (formaldehyde inactivated)Imiglucerase
go.drugbank.com/drugs/DB00053ApprovedInvestigationalHuman Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. … The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated with mannose residues.
Products: CEREZYME 400 U/10 ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ İÇİN TOZ, CEREZYME 400 UNITGemeprost
go.drugbank.com/drugs/DB08964ApprovedWithdrawnGemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. … It is not FDA-approved but available in Japan marketed as Preglandin.
Categories: Prostaglandins E, Prostaglandins E, SyntheticSynonyms: 16,16-Dimethyl-trans-delta(sup 2)-prostaglandin E1 methyl ester, 16,16-Dimethyl-trans-delta-2-PGE1 methyl esterThiosulfuric acid
go.drugbank.com/drugs/DB09499ApprovedInvestigational[A252827] Sodium thiosulfate is rapidly degraded in the stomach; therefore, it is normally administered through other routes, such as intravenous or topical. … [A252827] Sodium thiosulfate is approved for the treatment of acute cyanide poisoning[L310,L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]).
Mixtures: Sodium Polysulthionate, 5-mthf, Sodium polysulthionate, 5-methyltetrahydrofolateCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP2B6 Inducers