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Demegestone
go.drugbank.com/drugs/DB13857ExperimentalDemegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEtynodiol
go.drugbank.com/drugs/DB13866ExperimentalEtynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see DB008...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesFluticasone
go.drugbank.com/drugs/DB13867ApprovedInvestigationalWithdrawnFluticasone is a synthetic glucocorticoid available as 2 esters, DB08906 and DB00588 [FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications [FDA Label]. DB00588 was ...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesWIN 55212-2
go.drugbank.com/drugs/DB13950ExperimentalWIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It is a potent cannabino...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors1,2-dichlorobenzene
go.drugbank.com/drugs/DB13963ApprovedWithdrawn1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound by the presence of t...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesNomegestrol acetate
go.drugbank.com/drugs/DB13981ApprovedNomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMedical Cannabis
go.drugbank.com/drugs/DB14009InvestigationalThe use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical conditions as a wave of legalization in North America h...
Categories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein inhibitorsNabiximols
go.drugbank.com/drugs/DB14011InvestigationalNabiximols (tradename Sativex®) is a whole plant extract from the Cannabis species Cannabis sativa L. that has been purified into the active components CBD (cannabidiol) and THC (delta-9-tetrahydrocannabinol). For trademark purposes, pur...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsFosnetupitant
go.drugbank.com/drugs/DB14019ApprovedInvestigationalIn April 2018, the U.S. Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg) as an alte...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 SubstratesNepidermin
go.drugbank.com/drugs/DB14145InvestigationalProducts: HEBERPROT-P, HEBERPROT-P 75 MCG ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET