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Eprenetapopt
go.drugbank.com/drugs/DB11684InvestigationalEprenetapopt has been used in trials studying the treatment of Prostatic Neoplasms, Hematologic Neoplasms, and Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53.
Synonyms: 1-Azabicyclo(2.2.2)octan-3-one, 2-(hydroxymethyl)-2-(methoxymethyl)-, 2-hydroxymethyl-2-methoxymethyl-1-azabicyclo[2,2,2]octan-3-oneArketamine
go.drugbank.com/drugs/DB19150InvestigationalArketamine is under investigation in clinical trial NCT05414422 (A Randomized, Placebo-controlled, Double-blind Study to Assess Safety and Efficacy of PCN-101 in TRD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesSynonyms: Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (2r)-, Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+)-Serine
go.drugbank.com/drugs/DB00133ApprovedInvestigationalNutraceuticalA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.
Mixtures: AMINOMIX 2 NOVUM 1000 ML, AMINOMIX 2 NOVUM 1500 MLSynonyms: (S)-2-Amino-3-hydroxypropanoic acid, L-SerineZED-1227
go.drugbank.com/drugs/DB19208InvestigationalZED-1227 is under investigation in clinical trial NCT05305599 (Different Doses of ZED1227 vs. Placebo in NAFLD).
Synonyms: (2e,6s)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-1,2-dihydro-2-oxo-3-pyridinyl)amino)-6-(((1-methyl-1h-imidazol-5-yl)carbonyl)amino)-7-oxo-2-heptenoic acid methyl ester, Methyl (e,6s)-7-((1-(2-(2-ethylbutylamino)-2-oxo-ethyl)-2-oxo-3-pyridyl)amino)-6-((3-methylimidazole-4-carbonyl)amino)-7-oxo-hept-2-enoateCategories: Heterocyclic Compounds, 1-RingCystine
go.drugbank.com/drugs/DB00138ApprovedInvestigationalNutraceuticalWithdrawnA covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.
Synonyms: (R,R)-3,3'-dithiobis(2-aminopropanoic acid), β,β'-dithiodialanine(4S)-5-[[(1S)-1-Carboxy-2-cyclohexylethyl]amino]-4-[[(2S)-2-[[(3R)-4-cyclohexyl-2-oxo-3-(phenylmethoxycarbonylamino)butanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoic acid
go.drugbank.com/drugs/DB01984ExperimentalSynonyms: (4S)-5-[[(1S)-1-Carboxy-2-cyclohexylethyl]amino]-4-[[(2S)-2-[[(3R)-4-cyclohexyl-2-oxo-3-(phenylmethoxycarbonylamino)butanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoic acidQuinine
go.drugbank.com/drugs/DB00468ApprovedInvestigationalQuinine (GLS-1200) was also investigated in clinical trials for its efficacy in preventing SARS-CoV-2 infection (NCT04408183, terminated) and is planned to be evaluated for preventing sinusitis after endoscopic … It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
Mixtures: IRUDERM 1Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsRopidoxuridine
go.drugbank.com/drugs/DB06485InvestigationalRopidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR, which demonstrated a survival advantage in Phase II studies in anaplastic astrocytoma, a type of brain tumor.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-iodo-2-pyrimidinone-2'-deoxyribose, 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-IODOPYRIMIDIN-2(1H)-ONEMilacemide
go.drugbank.com/drugs/DB19525ExperimentalMilacemide is a small molecule drug. Milacemide has a monoisotopic molecular weight of 144.13 Da.
Synonyms: 2-(pentylamino)acetamide, Acetamide, 2-(pentylamino)-(5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide
go.drugbank.com/drugs/DB07397ExperimentalSynonyms: (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide