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Hydroxyacid-oxoacid transhydrogenase, mitochondrial
go.drugbank.com/bio_entities/BE0008675EnzymeHumansD,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities
Synonyms: HOTBentoquatam
go.drugbank.com/drugs/DB00516ApprovedBentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak. … Bentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin.
Clomifene
go.drugbank.com/drugs/DB00882ApprovedInvestigationalA triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Categories: Sex Hormones and Modulators of the Genital System, Estrogen Receptor ModulatorsRilpivirine
go.drugbank.com/drugs/DB08864ApprovedInvestigational[A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's … [L1030] On November 21, 2017, Rilpivirine, in combination with [dolutegravir], was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named
Categories: Antivirals used in combination for the treatment of HIV infectionsSynonyms: 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrileDutasteride
go.drugbank.com/drugs/DB01126ApprovedInvestigationalDutasteride was approved by the FDA in 2001 for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist [tamsulosin] to … enhance the therapeutic response.
Mixtures: Duoride-T 0.5mg/0.4mg Capsules, DUTASTERIDE E TAMSULOSINA DOCMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[A180826] The new semi-synthetic 2-morpholinoethyl ester of MPA was synthesized to avoid the gastrointestinal effects associated with the administration of MPA. … [A180826] In addition to the above uses, mycophenolate mofetil has also been studied for the treatment of nephritis and other complications of autoimmune diseases.
Synonyms: 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoateNorgestrel
go.drugbank.com/drugs/DB09389ApprovedHowever, only the levorotary enantiomer ([levonorgestrel]) is biologically active.
Categories: Sex Hormones and Modulators of the Genital SystemIsosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Synonyms: Dinitrato de isosorbidaProducts: DINITRATO DE ISOSORBIDE DE 40 MG, DINITRATO DE ISOSORBIDE TABLETAS 10MGAscorbyl phosphate
go.drugbank.com/drugs/DB11352ApprovedInvestigationalC that is readily absorbed into the skin with a hydrating effect on the skin [A27212]. … While ascorbyl phosphate salts provide a constant delivery of vitamin C into the skin, they also mediate an antioxidant action to act as a free radical scavenger and increases collagen production *in vitro
Mixtures: Le-Blen Vitamin C SerumGadopentetic acid
go.drugbank.com/drugs/DB00789ApprovedInvestigational(From Martindale, The Extra Pharmacopoeia, 30th ed, p706) … A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs.