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Displaying results 1931 - 1940 of 10000 in total
  1. Drug

    Denosumab

    go.drugbank.com/drugs/DB06643
    ApprovedInvestigational

    [A263066] An Denosumab biosimilar, Jubbonti, was approved for Health Canada in February 2024.[L52083]. … Two denosumab biosimilars—Wyost® (denosumab-bbdz) [L53063] and Jubbonti® (denosumab-bbdz)[L53058]—were approved by the FDA in March 2024 for all indications of the reference products Xgeva® and Prolia®

    Categories: Amino Acids, Peptides, and Proteins, Drugs Affecting Bone Structure and MineralizationProducts: XGEVA 120mg Solution for Injection, Prolia Solution for Injection 60mg Pre-filled Syringe
  2. Drug

    Levosulpiride

    go.drugbank.com/drugs/DB16021
    Investigational

    Categories: Benzamides and benzamide derivativesProducts: DISLEP® 25MG/ML GOTAS, LEPRIT®25MG TABLETA
  3. Drug

    Centella asiatica

    go.drugbank.com/drugs/DB14256
    Approved

    Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Ma Ti Cao Whole, Ji Xue Cao WholeMixtures: ACTS38 BoswelliaGel (100ml)
  4. Drug

    Fludeoxyglucose (18F)

    go.drugbank.com/drugs/DB09502
    ApprovedInvestigational

    It is administered by intravenous injection. … Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with

    Categories: Indicators and Reagents, Compounds used in a research, industrial, or household settingProducts: MON.FDG IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET, MOLTEK FDG IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET
  5. Drug

    Diethylamino hydroxybenzoyl hexyl benzoate

    go.drugbank.com/drugs/DB11269
    Approved

    Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated … Diethylamino hydroxybenzoyl hexyl benzoate was approved in Europe in 2005, and is also marketed in the U.S., South America, Mexico, Japan and Taiwan.

    Mixtures: Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types, Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types
  6. Drug

    Recombinant Bacterial ACE2 Receptors-like Enzyme

    go.drugbank.com/drugs/DB15741
    Investigational

    B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction. … B38-CAP is structured as a carboxypeptidase and derived from _Paenibacillus sp._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2

    Synonyms: B38-CAP
  7. Drug

    Tretinoin

    go.drugbank.com/drugs/DB00755
    ApprovedInvestigationalNutraceutical

    [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism. … and differentiation.

    Mixtures: OLIVIA QUIDO FIRM and FADE I, OLIVIA QUIDO FIRM and FADE IICategories: Retinoids for Topical Use in Acne, Cell Stimulants and Proliferants
  8. Target

    cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

    go.drugbank.com/bio_entities/BE0000631
    TargetHumans

    Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate (PubMed:10373451, PubMed:10393245, PubMed:17389385, PubMed:27058447). … May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition (PubMed:27058447)

    Polypeptides: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  9. Target

    2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2

    go.drugbank.com/bio_entities/BE0002203
    TargetHumans

    Polypeptides: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2
  10. Target

    TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

    go.drugbank.com/bio_entities/BE0005824
    TargetHumans

    Key adapter protein that plays an essential role in JNK and NF-kappa-B activation and proinflammatory cytokines production in response to stimulation with TLRs and cytokines (PubMed:22307082, PubMed:24403530 … In turn, MAPK14 phosphorylates TAB1 and inhibits MAP3K7/TAK1 activation in a feedback control mechanism (PubMed:14592977).

    Polypeptides: TGF-beta-activated kinase 1 and MAP3K7-binding protein 1