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Olipudase alfa
go.drugbank.com/drugs/DB12835ApprovedInvestigational[A251590] It was later approved by the European Commission on June 28, 2022 [L42740] and by the FDA on August 31, 2022.[L43145] … [A251590] Olipudase alfa gained its first global approval in Japan on March 28, 2022.
Fosinopril
go.drugbank.com/drugs/DB00492ApprovedInvestigationalFosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals … It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Categories: Agents Acting on the Renin-Angiotensin SystemProducts: Lin-fosinoprilFidanacogene elaparvovec
go.drugbank.com/drugs/DB16783ApprovedInvestigational[A32552] Disease severity is linked to the level of factor IX activity in the blood plasma, ranging from increased bleeding after injuries and surgical operations to spontaneous bleeding, hemorrhages in … [L46691] Hemophilia B is a rare X-linked genetic disorder characterized by abnormal coagulation due to dysfunctional coagulation factor IX with a male incidence estimated to be 1 in 30,000 male births
Anthralin
go.drugbank.com/drugs/DB11157ApprovedAnthralin is also known as dithranol. It is a main active ingredient in topical skin formulations for the treatment of psoriasis. … It is important to consider that the drug is relatively innocuous, yet effective, and systemic side effects have not been observed with this anthralin, in contrast to a wide variety of systemic and topical
Crotamiton
go.drugbank.com/drugs/DB00265ApprovedIt is miscible with alcohol and with methanol. … Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor.
Categories: Compounds used in a research, industrial, or household settingAvalglucosidase alfa
go.drugbank.com/drugs/DB16099ApprovedInvestigational[A232955] In clinical trials, avalglucosidase alfa improved lung function in patients with Pompe disease. … GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions.
Amlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine is commonly used in the treatment of high blood pressure and angina. … Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_.
Mixtures: Atorvalan comp. 10 mg/5 mg-Filmtabletten, Atorvalan comp. 10 mg/10 mg-FilmtablettenCategories: Angiotensin II Antagonists and Calcium Channel Blockers, Angiotensin II receptor blockers (ARBs) and calcium channel blockersChlorobutanol
go.drugbank.com/drugs/DB11386ApprovedVet approvedWithdrawnSimilar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone. … It also elicits sedative-hypnotic and weak local anesthetic actions in addition to antibacterial and antifungal properties.
Categories: Compounds used in a research, industrial, or household settingClonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD. … [L7237,L54536,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.[L7237]
Synonyms: 2,6-Dichloro-N-2-imidazolidinylidenebenzenamineCategories: Sympathomimetics in Glaucoma TherapyOzanimod
go.drugbank.com/drugs/DB12612ApprovedInvestigationalin MS therapy. … [L41524] In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.