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Displaying results 1941 - 1950 of 10000 in total
  1. Target

    Interleukin-7 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0010557
    TargetHumans

    Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP)

    Polypeptides: Interleukin-7 receptor subunit alphaSynonyms: IL-7 receptor subunit alpha
  2. Target

    Sphingosine 1-phosphate receptor 2

    go.drugbank.com/bio_entities/BE0012208
    TargetHumans

    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) (PubMed:10617617, PubMed:25274307). … Receptor for the chemokine-like protein FAM19A5 (PubMed:29453251). Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity).

    Polypeptides: Sphingosine 1-phosphate receptor 2Synonyms: S1P receptor 2, S1P receptor Edg-5
  3. Target

    N-formyl peptide receptor 2

    go.drugbank.com/bio_entities/BE0012843
    TargetHumans

    Differential signaling is also defined by receptor oligomerization state. … Pattern recognition G protein-coupled receptor (GPCR) that recognizes peptides with N-terminal formyl methionine, which are derived from invading pathogens or host mitochondria as pathogen or damage-associated

    Polypeptides: N-formyl peptide receptor 2Synonyms: LXA4 receptor, Lipoxin A4 receptor
  4. Drug

    Iodine

    go.drugbank.com/drugs/DB05382
    ApprovedInvestigational

    Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. … Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]

    Mixtures: Multi II IV Vi Tab, Multipack IISynonyms: I2
  5. Drug

    Alkaline Phosphatase

    go.drugbank.com/drugs/DB05768
    Investigational

    Alkaline Phosphatase (AP) is an oral treatment and has a very favorable side-effect profile. … AP only acts locally in the colon to reduce the continuous inflammation of the colon by endotoxin from Gram-negative bacteria and extracellular ATP in UC patients.

  6. Drug

    Maribavir

    go.drugbank.com/drugs/DB06234
    ApprovedInvestigational

    Maribavir is an inhibitor of the cytomegalovirus (CMV; HHV5) pUL97 kinase which is used to treat CMV infections in patients post-transplantation. … [A242557] Maribavir is novel in that it instead targets the CMV pUL97 kinase, thereby providing an effective alternative treatment option in cases of resistant infections.

  7. Drug

    Teduglutide

    go.drugbank.com/drugs/DB08900
    ApprovedInvestigational

    Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. … The significance of this substitution is that teduglutide is longer acting than endogenous GLP-2 as it is more resistant to proteolysis from dipeptidyl peptidase-4. FDA approved on December 21, 2012.

    Synonyms: Glucagon-like peptide II (2-glycine) (human)Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Ertugliflozin

    go.drugbank.com/drugs/DB11827
    ApprovedInvestigational

    Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. … [A31581] Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.[L48621]

    Categories: Drugs Used in Diabetes
  9. Drug

    Zonisamide

    go.drugbank.com/drugs/DB00909
    ApprovedInvestigational

    The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] … Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Ferric sulfate

    go.drugbank.com/drugs/DB11171
    Approved

    Ferric sulfate has the molecular formula of Fe2SO4, and it is a dark brown or yellow chemical agent with acidic properties. It is produced by the reaction of sulfuric acid and an oxidizing agent. … It is used in different fields such as dermatology, dentistry and it is thought to present hemostatic properties by interacting chemically with blood proteins.