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Filgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigationalIt has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … It is also used to manage severe chronic neutropenia and mobilize hematopoietic progenitor cells to the peripheral blood for collection by leukapheresis in patients undergoing peripheral blood progenitor
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: ZARZIO® 30 MU/0.5 ML SOLUCION INYECTABLE O PARA PERFUSION EN JERINGA PRECARGADAOxamniquine
go.drugbank.com/drugs/DB01096ApprovedAn anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. … Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs.
Categories: Quinoline Derivatives and Related Substances, Antiparasitic Products, Insecticides and RepellentsEndocarditis, Subacute Bacterial
go.drugbank.com/conditions/DBCOND0000330Drugs: Procaine benzylpenicillinSynonyms: Acute and subacute endocarditis, unspecifiedTakayasu Arteritis
go.drugbank.com/conditions/DBCOND0000704Drugs: PrednisoneSynonyms: Sclerosing aortitis AND arteritis, Idiopathic medial aortopathy AND arteriopathyCarbon monoxide
go.drugbank.com/drugs/DB11588ApprovedInvestigationaland other organs. … Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air.
Mixtures: Lung Diffusion Test Mix No Ne Co, Co-NE-O2-N2 MixtureSynonyms: COLuliconazole
go.drugbank.com/drugs/DB08933ApprovedInvestigationalLuliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. … It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. Luliconazole is also approved in Japan.
Categories: Imidazole and Triazole DerivativesMedrogestone
go.drugbank.com/drugs/DB09124ApprovedWithdrawnIt was conceived as an alternative for an orally effective contraceptive option.[A31526] It was developed by Ayerst, approved in Canada in 1969 and its current status is cancelled post-marketing. … [L1118] It was never approved by the FDA.
Mixtures: PRESOMEN CONTI 0.6MG/2MG, PRESOMEN CONTI 0.6MG/2MGCategories: medrogestone and estrogen, Genito Urinary System and Sex HormonesPapain
go.drugbank.com/drugs/DB11193ApprovedWithdrawnWhile it has been used for the treatment of inflammation and pain via topical administration, papain has also shown to have anthelmintic and tooth-whitening properties. … The enzyme is found to be localized in the skin of papaya, and is collected from slashed unripe papayas as a crude latex. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
Mixtures: Bromelain and Papain Tab, Herbalax Forte No 70 TabCategories: Enzymes and CoenzymesDrospirenone
go.drugbank.com/drugs/DB01395ApprovedInvestigationalSome studies have demonstrated a significantly increased risk and some demonstrating no risk of thromboembolic events. … [L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol] as an oral contraceptive therapy.
Mixtures: Lo-Zumandimine, Drospirenone and Ethinyl EstradiolCategories: drospirenone and estetrol, drospirenone and estrogenProtein C
go.drugbank.com/drugs/DB11312ApprovedInvestigationalAPC exerts its effect by inactivating essential components of the coagulation cascade (specifically factors V and VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot … It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to Activated Protein C (APC).
Mixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, Octaplex Powder and Solvent for Solution for InfusionCategories: Enzymes and Coenzymes, Blood and Blood Forming Organs