Search

Displaying results 1961 - 1970 of 1993 in total
  1. Target

    Integrin alpha-X

    go.drugbank.com/bio_entities/BE0009967
    TargetHumans

    Functions as a receptor of the erythrocyte-specific adhesion molecule ICAM4 and mediates erythrophagocytosis (PubMed:16985175) … Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses.

    Synonyms: Leukocyte adhesion receptor p150,95
  2. Target

    Protein S100-A6

    go.drugbank.com/bio_entities/BE0002950
    TargetHumans

    May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such a...

    Synonyms: Prolactin receptor-associated protein
  3. Drug

    Natural Killer Cell

    go.drugbank.com/drugs/DB15721
    Investigational

    The most standard and utilized source of NK cells is directly from the peripheral blood of a donor through leukapheresis: a technique where immune cells are separated from red blood cells.

  4. Target

    Prostaglandin E synthase 3

    go.drugbank.com/bio_entities/BE0002480
    TargetHumans

    Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory

    Synonyms: Progesterone receptor complex p23
  5. Target

    SLAM family member 7

    go.drugbank.com/bio_entities/BE0003492
    TargetHumans

    Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family.

    Synonyms: CD2-like receptor-activating cytotoxic cells
  6. Drug

    Simethicone

    go.drugbank.com/drugs/DB09512
    ApprovedInvestigational

    Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in ...

    Mixtures: ESPAVEN MD
  7. Target

    DNA-binding transcriptional dual regulator CRP

    go.drugbank.com/bio_entities/BE0002013
    TargetEscherichia coli (strain K12)

    A global transcription regulator, which plays a major role in carbon catabolite repression (CCR) as well as other processes. Binds cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5'-AAATGTGATCTAGATCACA...

    Synonyms: cAMP receptor protein
  8. Target

    Stabilin-1

    go.drugbank.com/bio_entities/BE0010944
    TargetHumans

    Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection.

    Synonyms: Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1
  9. Target

    Sodium-dependent phosphate transporter 2

    go.drugbank.com/bio_entities/BE0008680
    TransporterHumans

    Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion (PubMed:12205090, PubMed:15955065, PubMed:16790504, PubMed:17494632, PubMed:22327515, P...

    Synonyms: Gibbon ape leukemia virus receptor 2Function: signaling receptor activity
  10. Target

    C-type lectin domain family 10 member A

    go.drugbank.com/bio_entities/BE0016623
    TargetHumans

    Acts as a signaling receptor at the interface of APC-T cell interactions. … Acts as an endocytic pattern recognition receptor involved in antitumor immunity.

    Synonyms: DC-asialoglycoprotein receptor