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Cysteine
go.drugbank.com/drugs/DB00151ApprovedInvestigationalNutraceuticalA thiol-containing non-essential amino acid that is oxidized to form cystine.
Mixtures: Vamin N, AMINOSTERIL N-HEPA 8%Technetium Tc-99m sulfur colloid
go.drugbank.com/drugs/DB09397ApprovedThis is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray. … (intraperitoneal injection), is taken up by reticulocytes (intravenous injection), or enters the gastroesphageal tract (oral administration).
Tropisetron
go.drugbank.com/drugs/DB11699ApprovedInvestigationalWithdrawnTropisetron appears to be well tolerated with the most frequently reported adverse effect being headache. Extrapyramidal side effects are rare upon using tropisetron.
Futibatinib
go.drugbank.com/drugs/DB15149ApprovedInvestigational[A253193,A253198] As a novel inhibitor of FGFR, futibatinib was first approved by the FDA in September 2022 to treat different types of intrahepatic cholangiocarcinoma. … [L43347] On July 4, 2023, the European Commission granted Conditional Marketing Authorization for futibatinib for the treatment of cholangiocarcinoma.[L47800]
Janssen COVID-19 Vaccine
go.drugbank.com/drugs/DB15857ApprovedInvestigationalAs of June 2020, a Phase 1/2 clinical trial in adult humans was announced to evaluate the safety, immunogenicity, and efficacy of the ad26.COV.S vaccine in 1045 healthy adults between the ages of 18-55
Coagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100ApprovedIt is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell … Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology.
Lymecycline
go.drugbank.com/drugs/DB00256ApprovedInvestigationalWithdrawnIt is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. … Lymecycline is not marketed in the USA, however, equivalent drugs are available, such as minocycline and [tetracycline].[A19429,L13880]
Synonyms: N-Lysinomethyltetracycline, N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracyclineUlipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalThe exact mechanism of action for ulipristal is still currently debated, though there is evidence that it functions by inhibiting ovulation. … debated due to ethical concerns related to abortion (Rosato et al, 2016).
Technetium Tc-99m succimer
go.drugbank.com/drugs/DB09436ApprovedIt works by binding to the cortical region of the kidneys. Technetium Tc-99m succimer is used with gamma scintigraphy or single-photon emission computed tomography (SPECT). … [L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first approved by the FDA on February 23, 2022, under the market name NephroScan.[L40573]
Sodium zirconium cyclosilicate
go.drugbank.com/drugs/DB14048ApprovedInvestigationalSodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that … [L2933] The treatment effect was maintained for up to 12 months.[L2933]