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Displaying results 1971 - 1980 of 2454 in total
  1. Drug

    Medical Cannabis

    go.drugbank.com/drugs/DB14009
    Investigational

    The use of the plant species _Cannabis sativa_ and _Cannabis indica_, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical conditions as a

    Categories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein inhibitors
  2. Drug

    Nabiximols

    go.drugbank.com/drugs/DB14011
    Investigational

    Nabiximols (tradename Sativex®) is a whole plant extract from the Cannabis species Cannabis sativa L. that has been purified into the active components CBD (cannabidiol) and THC (delta-9-tetrahydrocannabinol). For trademark purposes, pur...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  3. Drug

    Fosnetupitant

    go.drugbank.com/drugs/DB14019
    ApprovedInvestigational

    In April 2018, the U.S. Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg) as an alte...

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates
  4. Drug

    Nepidermin

    go.drugbank.com/drugs/DB14145
    Investigational

    Products: HEBERPROT-P, HEBERPROT-P 75 MCG ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET
  5. Drug

    Nepicastat

    go.drugbank.com/drugs/DB12979
    Investigational

    Nepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.

    Categories: P-glycoprotein substrates
  6. Drug

    Mephedrone

    go.drugbank.com/drugs/DB13108
    Investigational

    Mephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  7. Drug

    Lusutrombopag

    go.drugbank.com/drugs/DB13125
    ApprovedInvestigational

    Lusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan). TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promot...

    Categories: P-glycoprotein substrates
  8. Drug

    Von Willebrand factor human

    go.drugbank.com/drugs/DB13133
    ApprovedInvestigational

    The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the sit...

    Mixtures: HAEMATE P, HAEMATE P
  9. Drug

    Ethyl chloride

    go.drugbank.com/drugs/DB13259
    ApprovedWithdrawn

    Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. I...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  10. Drug

    Naftopidil

    go.drugbank.com/drugs/DB12092
    Investigational

    Naftopidil has been investigated for the treatment of Disorder of Urinary Stent.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates