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Candesartan
go.drugbank.com/drugs/DB13919InvestigationalCandesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.
Synonyms: 2-ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acidCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesEstradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approvedEstradiol Valerate (also known as E2V) is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as t...
Mixtures: CYCLO PROGYNOVA N 2MG/0.15, CYCLO PROGYNOVA N 2MG/0.15Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPatent Blue
go.drugbank.com/drugs/DB13967ApprovedInvestigational[A32574] It has the chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene)-2,5-cyclohexadiene-1-ylidene)diethylammonium hydroxide.
Bromotheophylline
go.drugbank.com/drugs/DB14018ApprovedBromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the s...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesDexniguldipine
go.drugbank.com/drugs/DB14068ExperimentalCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesDL-alpha-Tocopherol
go.drugbank.com/drugs/DB14476ApprovedInvestigationalMixtures: Vitalipid N, Vitalipid NHydrocortisone valerate
go.drugbank.com/drugs/DB14544ApprovedVet approvedCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersEdetate disodium anhydrous
go.drugbank.com/drugs/DB14600ApprovedInvestigationalVet approvedEdetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsFilgotinib
go.drugbank.com/drugs/DB14845ApprovedInvestigationalRheumatoid arthritis (RA) is a chronic, autoimmune, systemic, and inflammatory disease that causes synovial joint symptoms and can limit range of motion in severe cases. The disease is associated with extra-articular manifestations, prog...
Categories: P-glycoprotein substratesMavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigationalMavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is ...
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Substrates