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Patent Blue is a dye used to label lymphatic vessels, arterial territories, and lymph nodes prior to biopsy in some cancers. Patent blue is aniline dye and it is one of the most common dyes used.
- Mechanism
- Curator reviewed · 2 references
The specific binding of patent blue allows it to freely travel in the breast lymphatics and allows staging with a less invasive alternative. Patent blue will form a complex with albumin which will be picked up by regional afferent lymphatics to identify sentinel lymph nodes. A sentinel lymph node is the first lymph node in a chain or group of lymph nodes that cancer is most likely to spread to. The determination of the sentinel lymph node allows the physician to stage cancer by observing if cancer has spread to the near lymph nodes.
- Primary indication
- Patent blue is used for marking lymphatic vessels and arterial territories as well as for sentinel lymph node prior to biopsy in patients with operable breast cancer and clinically negative lymph nodes in combination with...Curator reviewed · 5 structured indications
- Formula / weight
- C27H33N2O7S2 · 561.69 g/mol (avg)
- First approval
- Canada, 2013
- Also known as
- patent blue violet
Resolves to
DHAHKSQXIXFZJB-UHFFFAOYSA-OSMILESCCN(CC)C1=CC=C(C=C1)C(=C1C=CC(C=C1)=[N+](CC)CC)C1=C(C=C(C(O)=C1)S(O)(=O)=O)S(O)(=O)=OWhat you can answer from here — as of September 16, 2026
Which drugs share a target with Patent Blue, and which of those have an active Phase 3 trial?