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Nonacog beta pegol
go.drugbank.com/drugs/DB13933ApprovedInvestigationalNonacog beta pegol is a recombinant coagulation factor IX derivative. … Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa).
Categories: Blood Coagulation Factors, Enzymes and CoenzymesSynonyms: Coagulation Factor IX (Recombinant), GlycoPEGylatedFactor XIII (human)
go.drugbank.com/drugs/DB12909ApprovedInvestigationalOther drug products with similar structure and function to Factor XIII (human) include [DB09310], which is a recombinant form of the A subunit of human coagulation factor XIII. … Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation
Categories: Blood Coagulation Factors, Enzymes and CoenzymesSynonyms: Coagulation factor XIII, recombinant, Human coagulation factor XIIICatridecacog
go.drugbank.com/drugs/DB09310ApprovedOther drug products with similar structure and function to Coagulation Factor XIII A-Subunit (Recombinant) include [DB12909], which is a purified endogenous (human) form of coagulation factor XIII. … Compared to Coagulation Factor XIII A-Subunit (Recombinant), which is produced through recombinant DNA technology where the target protein is grown in yeast and then isolated, the human form is isolated
Categories: Blood Coagulation Factors, Blood and Blood Forming OrgansSynonyms: Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor), Recombinant Coagulation Factor XIIIProthrombin
go.drugbank.com/drugs/DB11311ApprovedInvestigationalProthrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with
Mixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, Octaplex Powder and Solvent for Solution for InfusionCategories: Blood Coagulation Factors, Enzymes and CoenzymesAntihemophilic factor human
go.drugbank.com/drugs/DB13192ApprovedInvestigationalAntihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential … Other drug products with similar structure and function to Antihemophilic factor human include [DB13999], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced
Synonyms: Human coagulation factor VIII, factor VIII, humanMixtures: von Willebrand Factor/Coagulation Factor VIII Complex (Human), von Willebrand Factor/Coagulation Factor VIII Complex (Human)Von Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalThe human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. … [L40049] As vWF is normally present in the blood as a stable complex with coagulation factor III, therapeutic vWF products are also available as a combination product with [antihemophilic factor human]
Synonyms: Human von willebrand factor, Von Willebrand factor humanMixtures: von Willebrand Factor/Coagulation Factor VIII Complex (Human), von Willebrand Factor/Coagulation Factor VIII Complex (Human)Antihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalAntihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated … PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529].
Categories: Blood Coagulation Factors, Human Antihemophilic FactorsSynonyms: Antihemophilic Factor (Recombinant), PEGylated, antihemophilic factor (recombinant), PEGylated-auclHyaluronidase (human recombinant)
go.drugbank.com/drugs/DB06205ApprovedInvestigationalA purified preparation of the enzyme recombinant human hyaluronidase. … Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase
Synonyms: Hyaluronidase human recombinant, Hyaluronidase (human recombinant)Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansVonicog alfa
go.drugbank.com/drugs/DB12872ApprovedInvestigationalVonicog alfa is a recombinant human von Willebrand factor (rVWF) produced from Chinese hamster ovary cells. … [A264389] Vonicog alfa works to reduce bleeding events and bleeding times in patients with vWD, who have deficiencies in VWF.[A264389]
Categories: von Willebrand FactorSynonyms: Von willebrand factor, recombinant, human, (618-THREONINE,709-ASPARTIC ACID)VON WILLEBRAND FACTOR HOMO SAPIENS (1381A>T,1472H>D VARIANT) BLOOD COAGULATION FACTOREfmoroctocog alfa
go.drugbank.com/drugs/DB11607ApprovedInvestigationalEfmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII … VIII, but does not contain the B-domain, which has no known biological function, and [DB13192], which is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits.
Synonyms: Coagulation factor VIII recombinant immunoglubulin g1 fusion protein, Antihemophilic factor (recombinant, FC fusion protein)Categories: Human Antihemophilic Factors