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Sulindac
go.drugbank.com/drugs/DB00605ApprovedInvestigationalSulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditi...
Synonyms: cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid, (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acidProducts: BIO-DAC, Nu-sulindac Tab 150mgClonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD. Clonidine was granted FDA approval on 3 September 1974.
Synonyms: 2,6-Dichloro-N-2-imidazolidinylidenebenzenamineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesArbutin
go.drugbank.com/drugs/DB11217ApprovedExtracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal di...
Synonyms: p-hydroxyphenyl β-D-glucoside, p-hydroxyphenyl β-D-glucopyranosideMixtures: OHUI White Extreme Illuminating Pact No.10, OHUI White Extreme Illuminating Pact No.10Cetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalAllergic rhinitis is associated with multiple missed or unproductive days at work and school, problems with sleep, and other difficulties with day to day activities for many individuals [A175057].
Mixtures: VERACETAM NF CAPSULAS, All Day Allergy DCategories: P-glycoprotein inhibitors, P-glycoprotein substratesPolyethylene glycol
go.drugbank.com/drugs/DB09287ApprovedInvestigationalVet approvedPolyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a rati...
Mixtures: Gavilyte-NCategories: P-glycoprotein inhibitorsOlopatadine
go.drugbank.com/drugs/DB00768ApprovedOlopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine work...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: OLO-A-DAY, Pataday Twice A Day ReliefNifedipine
go.drugbank.com/drugs/DB01115ApprovedInvestigationalNifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972....
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: Nu-nifedipine-PA, Nu-nifedipine-PA - Prolonged Action TabAluminum chloride
go.drugbank.com/drugs/DB11081ApprovedInvestigationalAluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. It is used in various chemical applications as a Lewis ...
Products: ZeroSweat 3 DAY PROTECTION ANTIPERSPIRANT, Duradry PMAmifampridine
go.drugbank.com/drugs/DB11640ApprovedIt is currently used as the first-line symptomatic treatment for LEMS in adult patients and is ideally given as oral tablets in divided doses, three or four times a day. … Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium
Synonyms: DAP, 3,4-DAPPindolol
go.drugbank.com/drugs/DB00960ApprovedInvestigationalPindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythm...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: Nu-pindol Tab 5mg, Nu-pindol Tab 10mg