Search

Displaying results 191 - 200 of 7187 in total
  1. Drug

    RBIO-101

    go.drugbank.com/drugs/DB18425
    Experimental

    RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein.

    Synonyms: recombinant adeno-associated virus vector encoding human CYP4V2 protein
  2. Drug

    GX-19 Vaccine

    go.drugbank.com/drugs/DB15891
    Investigational

    The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758]. … As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].

    Synonyms: DNA vaccine expressing SARS-CoV-2 S-protein antigen
  3. Drug

    Efprezimod alfa

    go.drugbank.com/drugs/DB16448
    Investigational

    CD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem cell transplantation in leukemia patients.

    Synonyms: Human CD24 and human IgG Fc Fusion Protein
  4. Drug

    Bexagliflozin

    go.drugbank.com/drugs/DB12236
    ApprovedInvestigational

    Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor. … [A256423,L44758] In January 2023, bexagliflozin was approved by the FDA for the treatment of adults with type 2 diabetes.

    Categories: Sodium-Glucose Transport Proteins, antagonists & inhibitors, P-glycoprotein substratesSynonyms: D-glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-, (1s)-, (2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  5. Drug

    LNS-8801

    go.drugbank.com/drugs/DB18091
    Investigational

    Synonyms: G 1 (g protein-coupled estrogen receptor agonist), Ethanone, 1-((3ar,4s,9bs)-4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3h-cyclopenta(c)quinolin-8-yl)-, rel-
  6. Drug

    Paclitaxel

    go.drugbank.com/drugs/DB01229
    ApprovedInvestigationalVet approved

    Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. … Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel

    Synonyms: paclitaxel protein-bound particles, Paclitaxel protein-bound particles for injection suspensionCategories: Proteins, Amino Acids, Peptides, and Proteins
  7. Drug

    Exagamglogene autotemcel

    go.drugbank.com/drugs/DB15572
    ApprovedInvestigational

    Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe … [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease in HbS.

    Synonyms: Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated, gene editing consisting of a guide RNA (gRNA)
  8. Drug

    Deslanoside

    go.drugbank.com/drugs/DB01078
    Approved

    Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Deacetyllanatoside C, Desacetyllanatoside C
  9. Drug

    Verpasep caltespen

    go.drugbank.com/drugs/DB04959
    Investigational

    Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from _Mycobacterium bovis_, and the human papilloma viral (HPV) protein E7. … E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes.

    Synonyms: Heat-shock protein HSP 65 (Mycobacterium BCG) fusion protein with transcription factor E7 (human papillomavirus 16), Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7
  10. Drug

    Zalifrelimab

    go.drugbank.com/drugs/DB15632
    Investigational

    Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).

    Synonyms: A human monoclonal antibody targeting cytotoxic T lymphocyte associated protein 4 (ctla4), Immunoglobulin G1-kappa, anti-(homo sapiens CTLA4 (cytotoxic tlymphocyte-associated protein 4, cd152))