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Povidone-iodine
go.drugbank.com/drugs/DB06812ApprovedInvestigationalPovidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Indu...
Mixtures: P-Care X, P-Care MProducts: Nex Iodio P2, JOD POLYVID WUND U BRA I PTavapadon
go.drugbank.com/drugs/DB14899ApprovedTavapadon is an oral non-ergot dopamine agonist that acts as a selective partial agonist at the dopamine D1 and D5 receptors. It is used to treat Parkinson's disease in adults. The FDA approved tavapadon in September 2026 for the treatme...
Synonyms: PF-06649751Categories: Cytochrome P-450 CYP3A Inducers, P-glycoprotein substratesInsulin glargine
go.drugbank.com/drugs/DB00047ApprovedInvestigationalThe resulting protein is soluble at pH 4 and forms microprecipitates at physiological pH 7.4 allowing for the slow release of small amounts of insulin glargine, giving the drug a long duration of action … As a result, people with T1D rely primarily on exogenous forms of insulin, such as insulin glargine, to lower glucose levels in the blood.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersAcetaminophen
go.drugbank.com/drugs/DB00316ApprovedInvestigationalAcetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antip...
Mixtures: ConRx PM, Relief-PECategories: P-glycoprotein inhibitors, P-glycoprotein substratesDaprodustat
go.drugbank.com/drugs/DB11682ApprovedInvestigationalDaprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK. Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent in...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsPolysorbate 80
go.drugbank.com/drugs/DB11063ApprovedInvestigationalPolysorbate, a substance formulated by the reaction of sorbitan fatty acid ester (a nonionic surfactant) with ethylene oxide, is used in many foreign countries, including the U.S. and the EU, where it acts as an emulsifier, a solubilizer...
Mixtures: Refresh Digital PFCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsMagnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Mixtures: Isolyte S pH 7.4, DIANEAL PD-1 with DextroseSonrotoclax
go.drugbank.com/drugs/DB18753ApprovedInvestigational[L56193,A275521] Sonrotoclax was rationally designed as a BH3 mimetic with a shallow and broad interaction with the P2 pocket of BCL-2, achieved through a novel 7-azaspiro[3.5]nonane linker; this binding
Categories: Cytochrome P-450 CYP2C8 Substrates, Cytochrome P-450 CYP3A InhibitorsLactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedA normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and ...
Mixtures: DIANEAL PD-1 with Dextrose, DIANEAL PD-1 with DextroseVecabrutinib
go.drugbank.com/drugs/DB16657InvestigationalVecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers).