Search
Endometrial Hyperplasia
go.drugbank.com/conditions/DBCOND0001317Synonyms: Complex endometrial hyperplasia (disorder)Mitochondrial ATP synthase F1 domain
go.drugbank.com/bio_entities/BE0010209TargetEnzymeHumansATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Part of the complex F(0) domain (PubMed:37244256).
Polypeptides: ATP synthase F(1) complex subunit alpha, mitochondrial, ATP synthase F(1) complex subunit beta, mitochondrialLys-63-specific deubiquitinase BRCC36
go.drugbank.com/bio_entities/BE0009071TargetHumansMediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex (PubMed:19214193). … Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites
Synonyms: BRCA1-A complex subunit BRCC36, BRISC complex subunit BRCC36Cytochrome b
go.drugbank.com/bio_entities/BE0004428TargetPlasmodium falciparumComponent of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. … The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Synonyms: Complex III subunit 3, Complex III subunit IIICytochrome c1, heme protein, mitochondrial
go.drugbank.com/bio_entities/BE0003854TargetHumansThe respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
Synonyms: Complex III subunit 4, Complex III subunit IVCytochrome b
go.drugbank.com/bio_entities/BE0000938TargetHumansComponent of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. … The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis
Synonyms: Complex III subunit 3, Complex III subunit IIIPseudoazurin
go.drugbank.com/bio_entities/BE0001952TargetAlcaligenes faecalisThis soluble electron transfer copper protein is required for the inactivation of copper-containing nitrite reductase in the presence of oxygen.
Synonyms: Blue copper proteinFunction: copper ion bindingTumor susceptibility gene 101 protein
go.drugbank.com/bio_entities/BE0019070TargetHumansComponent of the ESCRT-I complex, a regulator of vesicular trafficking process. … Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation.
Synonyms: ESCRT-I complex subunit TSG101NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
go.drugbank.com/bio_entities/BE0000367TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (PubMed:27626371, PubMed:32385911, PubMed:33153867). … Complex I functions in the transfer of electrons from NADH to the respiratory chain (PubMed:27626371). The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:27626371)
Synonyms: Complex I-19kD, Complex I-PGIV