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Zenocutuzumab
go.drugbank.com/drugs/DB15559ApprovedInvestigational[L56179] This approval was expedited following receipt of an FDA Commissioner’s National Priority Voucher.
Ciclesonide
go.drugbank.com/drugs/DB01410ApprovedInvestigationalCiclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Pemivibart
go.drugbank.com/drugs/DB18720InvestigationalPemivibart (Pemgarda) is a human IgG1 monoclonal antibody targeting the SARS-CoV-2 spike protein receptor binding domain.
Clofazimine
go.drugbank.com/drugs/DB00845ApprovedInvestigationalWithdrawnClofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as dapsone, for the treatment of leprosy. It was originally described in 1957 and was the prototypical riminophenazine dye -...
Bromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalBromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducin...
Dihydroergotamine
go.drugbank.com/drugs/DB00320ApprovedInvestigationalRecent improvements have been made in the design of intranasal delivery devices allowing for greater delivery of dihydroergotamine solution to the vasculature-rich upper nasal cavity.
Categories: Serotonin Receptor Agonists, Adrenergic alpha-1 Receptor AntagonistsDL-alpha-Tocopherol
go.drugbank.com/drugs/DB14476ApprovedInvestigationalMixtures: Eden With Vitamins A, C, and EAfamelanotide
go.drugbank.com/drugs/DB04931Approved[L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125]
Categories: Melanocortin Receptor Agonists, Melanocortin 1 Receptor (MC1-R) AgonistsMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalMetformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabe...
Damoctocog alfa pegol
go.drugbank.com/drugs/DB14700ApprovedInvestigationalIn recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval.