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Fluphenazine
go.drugbank.com/drugs/DB00623ApprovedA phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine, 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanolMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527] … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.
Mixtures: IMPLICOR FILM-COATED TABLET 25 mg/5 mg, IMPLICOR FILM-COATED TABLET 25 mg/7.5 mgCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such … It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity.
Synonyms: (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol, (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanolMixtures: SOPRANO 10 MG/25 MG FILM TABLET, 50 ADET, SOPRANO 10 MG/25 MG FILM TABLET, 30 ADETEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalIn a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein. … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor.
Synonyms: 40-O-(2-hydroxyethyl)-rapamycin, 42-O-(2-Hydroxyethyl)rapamycinCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexMethyl salicylate
go.drugbank.com/drugs/DB09543ApprovedInvestigationalVet approvedIt is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic in mouthwash solutions. … For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments.
Mixtures: OTACI TERMAL POMAD, 25 G, Dfs 1.5%/ms 25%/menth 6%/cap 0.025% PakCategories: Compounds used in a research, industrial, or household settingPaclitaxel
go.drugbank.com/drugs/DB01229ApprovedInvestigationalVet approvedUsed as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel … Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSynonyms: 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine, -HYDROXY-, (2AR,4S,4AS,6R,9S,11S,12S,12AR,12BS)-6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA(3Griseofulvin
go.drugbank.com/drugs/DB00400ApprovedVet approvedAn antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP1A2 InducersInternational brands: Grison-250, S-FulvinLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalmake it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: 6-UR, CEUMID® CONCENTRADO PARA SOLUCIÓN PARA PERFUSIÓN 500 MG / 5 MLEtoposide
go.drugbank.com/drugs/DB00773ApprovedInvestigationalAccumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. … A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one, 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)Etodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedEtodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties.
Mixtures: ETOTIO 400 MG/8 MG FILM TABLET, 20 ADET, S-ETODUO 150/300 MG FİLM KAPLI TABLET, 20 ADETCategories: COX-2 Inhibitors, Heterocyclic Compounds, 2-Ring