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Displaying results 191 - 200 of 10000 in total
  1. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US. … [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527]

    Mixtures: IMPLICOR 50MG/5MG FILM-COATED TABLETS, IMPLICOR 50MG/7.5MG FILM-COATED TABLETSProducts: Gen-metoprolol Tablets 100mg, Gen-metoprolol Tablets 50mg
  2. Drug

    Oxaliplatin

    go.drugbank.com/drugs/DB00526
    ApprovedInvestigational

    [A260396] However, due to the structure of oxaliplatin, its adducts make the binding of mismatch repair protein to DNA harder compared to cisplatin or carboplatin's adducts, resulting in greater cytotoxic … Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect.

    Synonyms: (SP-4-2-(1R-TRANS))-(1,2-CYCLOHEXANEDIAMINE-N,N')(ETHANEDIOATO(2-)-O,O')PLATINUMProducts: OXALIPLATINO SUN PHARMACEUTICAL INDUSTRIES EUROPE, Oxaliplatin Hospira 5mg/mL, 50mg/10mL
  3. Drug

    Niacin

    go.drugbank.com/drugs/DB00627
    ApprovedInvestigationalNutraceutical

    Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.

    Mixtures: Pro Enz Tab, Ni-C-E-LE PlusCategories: Vitamin B Complex
  4. Drug

    Ertugliflozin

    go.drugbank.com/drugs/DB11827
    ApprovedInvestigational

    [A31581] Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.[L48621]

    Mixtures: Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated Tablets, Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated TabletsCategories: Drugs Used in Diabetes
  5. Drug

    Metoclopramide

    go.drugbank.com/drugs/DB01233
    ApprovedInvestigational

    It is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system.

    Synonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideProducts: METOPRAX 10 MG/2 ML IM/IV ENJ. COZ. ICEREN AMPUL, 5 ADET, Reglan Tab 10mg
  6. Drug

    Thiamine

    go.drugbank.com/drugs/DB00152
    ApprovedInvestigationalNutraceuticalVet approved

    Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. … Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.

    Mixtures: Thiamine HCl 100mg W C 20mg, Supravite 10ml AmpouleCategories: Vitamin B Complex
  7. Drug

    Sibutramine

    go.drugbank.com/drugs/DB01105
    ApprovedIllicitWithdrawn

    Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. … In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.

    Products: SIBESY(R)10MG CAPSULAS, CONTROLEX 10MG CAPSULAS
  8. Drug

    Citrus bioflavonoids

    go.drugbank.com/drugs/DB14586
    Approved

    Synonyms: Hesperidin complexMixtures: Vitamin C Wafers 100mg, Pro Enz Tab
  9. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. … [A190273] Nifedipine was granted FDA approval on 31 December 1981.[L11383]

    Mixtures: NIF TEN 50, NIF-TEN CAPSULEProducts: Gen Nifedipine Cap 10mg USP, ADALAT 10MG
  10. Drug

    Terazosin

    go.drugbank.com/drugs/DB01162
    ApprovedInvestigational

    Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate[A176837].

    Mixtures: Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg, Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mgCategories: Drugs Used in Benign Prostatic Hypertrophy