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Canakinumab
go.drugbank.com/drugs/DB06168ApprovedInvestigationalClinical trials have established the administration of canakinumab every 2 weeks to be safe and effective, offering a considerable advantage over the existing treatment with the human IL-1 receptor antagonist … Canakinumab binds to human IL-1β and neutralizes its inflammatory activity by blocking its interaction with IL-1 receptors, but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra).
Products: ILARIS® SOLUCIÓN INYECTABLE 150 MG/ ML, İLARİS 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADETToripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigationalOne mechanism by which this occurs is through the overexpression of programmed cell death ligand (PD-L1)[A261506] - the binding of PD-L1 (and PD-L2) to its target receptor (PD-1) results in the inhibition … [L48681] Toripalimab is a selective, recombinant, humanized IgG4 monoclonal antibody targeted against the PD-1 receptor.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsOxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigationalOxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to seve...
Mixtures: Xartemis XR, Xartemis XRCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTilmicosin
go.drugbank.com/drugs/DB11471InvestigationalVet approvedTilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
Categories: P-glycoprotein substratesProducts: PF TILMICOSIN PREMIX 20% W/W POWDER, JinPlus 250 mg/ml Oral LiquidCaspofungin
go.drugbank.com/drugs/DB00520ApprovedInvestigationalCaspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans, -3-hydroxy-L-proline cyclic (6-1)-peptideMagnesium carbonate
go.drugbank.com/drugs/DB09481ApprovedMagnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].
Mixtures: MAGCAR 680 MG+80 MG/5 ML SÜSPANSİYON, 100 ML, RENNIE 680 MG/80 MG/5 ML SUSPANSIYON, 100 MLTolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedTolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm.
Products: ProClearz Fungi-Cide PM, Scholls Odor-X Foot and SneakerCemiplimab
go.drugbank.com/drugs/DB14707ApprovedInvestigationalBy blocking PD-1, cemiplimab works to enhance T cell-mediated antitumour responses. … Cemiplimab is a fully human monoclonal antibody that works against programmed death receptor-1 (PD-1), which is a negative regulator of T cell function.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsTheophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalA methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine recep...
Mixtures: TURKFLEKS TEOFİLİN 0,2 G+4,5 G/100 ML IV İNFÜZYON İÇİN ÇÖZELTİ, 100 ML SETLİ, TURKFLEKS TEOFİLİN 0,4 G+22,5 G/500 ML IV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETSİZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesOxyquinoline
go.drugbank.com/drugs/DB11145ApprovedInvestigationalVet approvedOxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Mixtures: Fem pH