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  1. Pathway

    Hyperphenylalaninemia Due to 6-Pyruvoyltetrahydropterin Synthase Deficiency (ptps)

    smpdb.ca/view/SMP0125585
    Disease

    BH4-deficient hyperphenylalaninemia has several causes. One such cause is a PTS deficiency resultant from a genetic mutation. (In particular, a mutation in the gene encoding 6-pyruvoyl-tetrahydropterin synthase.) The mutation is autosoma...

    Drugs: Phenylalanine · Tyrosine · NADH · Sapropterin · Iron · Zinc +3 more
  2. Drug

    Ganciclovir

    go.drugbank.com/drugs/DB01004
    ApprovedInvestigational

    Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: CYMEVENE 500MG powder for concentrate for solution for infusion, HP-Ganciclovir 500 mg powder for concentrate for solution for infusion
  3. Drug

    Mometasone furoate

    go.drugbank.com/drugs/DB14512
    ApprovedInvestigationalVet approved

    Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295]. … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295].

    Mixtures: Hyaluronic Acid Sodium Salt 2% / Mometasone Furoate 0.1% / Niacinamide 4%, M-FURO MANT % 0.1 + % 1 KREM, 20GCategories: Corticosteroids for inhalation use, Drugs for Obstructive Airway Diseases
  4. Drug

    Sodium lauryl sulfate

    go.drugbank.com/drugs/DB00815
    Approved

    It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity. … Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl.

    Mixtures: For SopeCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Belimumab

    go.drugbank.com/drugs/DB08879
    ApprovedInvestigational

    [L42630] Belimumab was first approved by the FDA on March 9, 2011,[A251495] making it the newest drug to be approved for the treatment of SLE in more than 50 years. … [A251520] It is currently used to treat SLE and lupus nephritis.[L42630]

    Products: Benlysta Powder for Solution for Infusion 400mg, Benlysta Powder for Solution for Infusion 120mg
  6. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … It is also used to manage severe chronic neutropenia and mobilize hematopoietic progenitor cells to the peripheral blood for collection by leukapheresis in patients undergoing peripheral blood progenitor

    Synonyms: Tbo-filgrastimProducts: NUFIL SAFE, Zarzio 30 MU/0.5 ml solution for injection or infusion
  7. Drug

    Cefepime

    go.drugbank.com/drugs/DB01413
    ApprovedInvestigational

    [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical … Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Cefevon powder for solution for injection 2g/vial, ROXIPIME POWDER FOR SOLUTION FOR INJECTION 2G/VIAL
  8. Drug

    Bromus inermis pollen

    go.drugbank.com/drugs/DB10355
    Approved

    Bromus inermis pollen is the pollen of the Bromus inermis plant. Bromus inermis pollen is mainly used in allergenic testing.

    Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized GrassesProducts: Soft Cheat Brome
  9. Drug

    Sodium zirconium cyclosilicate

    go.drugbank.com/drugs/DB14048
    ApprovedInvestigational

    [L2933] The treatment effect was maintained for up to 12 months.[L2933] … Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that

    Categories: Drugs for Treatment of Hyperkalemia and Hyperphosphatemia, Compounds used in a research, industrial, or household settingProducts: LOKELMA POWDER FOR ORAL SUSPENSION 5G, LOKELMA POWDER FOR ORAL SUSPENSION 10G
  10. Drug

    Colistimethate

    go.drugbank.com/drugs/DB01111
    ApprovedInvestigationalVet approved

    Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. … Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.

    Products: Colomycin Injection 1 million International Units, POWDER FOR SOLUTION FOR INJECTION, INFUSION, OR INHALATION, Colistimethate for Injection, USP