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Itopride
go.drugbank.com/drugs/DB04924InvestigationalItopride is a dopamine D2 antagonist with acetylcholinesterase inhibitory actions.
Categories: Alimentary Tract and MetabolismSynonyms: N-(p-(2-(Dimethylamino)ethoxy)benzyl)veratramideParnaparin
go.drugbank.com/drugs/DB09260ApprovedParnaparin is an heparin of low molecular weight with antithrombotic effects.
Categories: Heparin and similars, Blood and Blood Forming OrgansProducts: FLUXUM 0.3 ML 3200 IU 2 HAZIR SIRINGA, FLUXUM 0.3 ML 3200 IU 6 HAZIR SIRINGATopotecan
go.drugbank.com/drugs/DB01030ApprovedInvestigationalAn antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Categories: Antineoplastic and Immunomodulating Agents, Topoisomerase I InhibitorsProducts: TOPOXIN 4 MG IV INF.ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, HYCAMTIN IV LİYOFİLİZE TOZ İÇEREN ENJEKTABL FLAKON, 1 ADETTirabrutinib
go.drugbank.com/drugs/DB15227InvestigationalTirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: 6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-oneReviparin
go.drugbank.com/drugs/DB09259Approved[A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation by the FDA.[L1469] … [A32019] It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa.
Categories: Heparin and similars, Blood and Blood Forming OrgansProducts: CLIVARIN 5726 IE A XA/MLPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
go.drugbank.com/bio_entities/BE0005530TargetHumansMay be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. … In motile cells, suppresses the formation of lateral pseudopods and thereby promotes cell polarization and directed movement (PubMed:22279049).
Polypeptides: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENSynonyms: Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1Iloprost
go.drugbank.com/drugs/DB01088ApprovedInvestigationalIloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. … [A263316] Iloprost is available as an inhaled solution and intravenous formulations. It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151]
Categories: Blood and Blood Forming OrgansSynonyms: (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acidBenserazide
go.drugbank.com/drugs/DB12783ApprovedInvestigationalA decarboxylase inhibitor like benserazide is consequently an effective compound to combine with levadopa as it is incapable of crossing the blood-brain barrier itself but acts to prevent the formation … combination in the form of levodopa and carbidopa.
Mixtures: LEVOBENS TEVA 100MG/25MG, RESTEX 100MG/25MG RETARDIEAzelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigationalAzelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic … allergic rhinitis in patients 6 years of age and older.
Mixtures: Dymista Nasal Spray 137mcg/50mcg, N-S-4Categories: Decongestants and AntiallergicsRecurrent or Metastatic Head and Neck Squamous Cell Carcinoma
go.drugbank.com/conditions/DBCOND0081226Drugs: NivolumabSynonyms: Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma