This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Parnaparin is a low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis.
- Generic Name
- Parnaparin
- DrugBank Accession Number
- DB09260
- Background
Parnaparin is an heparin of low molecular weight with antithrombotic effects.
- Type
- Small Molecule
- Groups
- Approved, Investigational
- Synonyms
- Parnaparin sodium
Pharmacology
- Indication
Used in the prevention and treatment of venous thromboembolism (deep vein thrombosis and pulmonary embolism) and in the treatment of myocardial infarction.
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- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAbciximab The risk or severity of bleeding can be increased when Abciximab is combined with Parnaparin. Acebutolol The risk or severity of hyperkalemia can be increased when Acebutolol is combined with Parnaparin. Aceclofenac The risk or severity of bleeding and hemorrhage can be increased when Aceclofenac is combined with Parnaparin. Acemetacin The risk or severity of bleeding and hemorrhage can be increased when Parnaparin is combined with Acemetacin. Acenocoumarol The risk or severity of bleeding can be increased when Acenocoumarol is combined with Parnaparin. Acetylsalicylic acid Acetylsalicylic acid may increase the anticoagulant activities of Parnaparin. Albutrepenonacog alfa The therapeutic efficacy of Albutrepenonacog alfa can be decreased when used in combination with Parnaparin. Alclofenac The risk or severity of bleeding and hemorrhage can be increased when Alclofenac is combined with Parnaparin. Aldesleukin The risk or severity of bleeding can be increased when Parnaparin is combined with Aldesleukin. Alemtuzumab The risk or severity of bleeding can be increased when Parnaparin is combined with Alemtuzumab. 
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- Avoid herbs and supplements with anticoagulant/antiplatelet activity. Examples include garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba.
Products
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Categories
- ATC Codes
- B01AB07 — Parnaparin
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- U6K360XMIU
- CAS number
- 9005-49-6
- InChI Key
- Not Available
- InChI
- Not Available
- IUPAC Name
- Not Available
- SMILES
- Not Available
References
- General References
- Maugeri N, Di Fabio G, Barbanti M, de Gaetano G, Donati MB, Cerletti C: Parnaparin, a low-molecular-weight heparin, prevents P-selectin-dependent formation of platelet-leukocyte aggregates in human whole blood. Thromb Haemost. 2007 Jun;97(6):965-73. [Article]
- External Links
- PubChem Substance
- 347910424
- 69528
- Wikipedia
- Parnaparin_sodium
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Completed Treatment Thrombophlebitis 1 3 Terminated Treatment Infertility / Low Molecular Weight Heparin 1 3 Terminated Treatment Retinal Vein Occlusion 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection Subcutaneous Injection, solution Subcutaneous 12800 IU/ml Injection, solution Subcutaneous 3200 IU/0.3ml Injection, solution Subcutaneous 4250 IU/0.4ml Injection, solution Subcutaneous 6400 IU/0.6ml Injection, solution Subcutaneous 8500 IU/0.8ml Injection Subcutaneous 3200 iu Injection Subcutaneous 4250 iu Injection Subcutaneous 6400 iu Injection, solution Subcutaneous - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at October 26, 2015 17:08 / Updated at May 05, 2021 20:31