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Ponatinib
go.drugbank.com/drugs/DB08901ApprovedInvestigationalPonatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Magnesium Aluminum Silicate
go.drugbank.com/drugs/DB11230ApprovedWithdrawnIt is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant … It also has antacid properties and is used as a component of some over the counter antacid medications.
Acarbose
go.drugbank.com/drugs/DB00284ApprovedInvestigationalAcarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. … Acarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes.
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
go.drugbank.com/bio_entities/BE0000493TargetHumansPlays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:30879903 … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor
Synonyms: Complex I-75kDTranslocation protein SEC62
go.drugbank.com/bio_entities/BE0009211TargetPlasmodium falciparum (isolate 3D7)Synonyms: Secretory complex protein 62Shark liver oil
go.drugbank.com/drugs/DB11088ApprovedThe 3 main targeted species are the deep sea shark (Centrophorus squamosus), the dogfish (Sqaulus acanthias), and the basking shark (Cetorhinus maximus). … Shark oil is extracted from the livers of sharks, which can account for up to 25% of their total body weight.
Temafloxacin
go.drugbank.com/drugs/DB01405ApprovedWithdrawnIt was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three … Temafloxacin is an antibiotic agent belonging to the fluoroquinolone drug class.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseOlutasidenib
go.drugbank.com/drugs/DB16267ApprovedInvestigational[A254736,A254741] Olutasidenib is orally bioavailable and capable of penetrating the blood-brain barrier, and is also being evaluated for the treatment of myelodysplastic syndrome (MDS), as well as solid … [L44256,L44261] It is indicated for the treatment of relapsed or refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an FDA-approved test.
Synonyms: (s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile, 2-pyridinecarbonitrile, 5-(((1s)-1-(6-chloro-1,2-dihydro-2-oxo-3-quinolinyl)ethyl)amino)-1,6-dihydro-1-methyl-6-oxo-Hexetidine
go.drugbank.com/drugs/DB08958ApprovedWithdrawnIt is used as a 0.1% mouthwash for local infections and oral hygiene.
Categories: Genito Urinary System and Sex HormonesInfluenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated)
go.drugbank.com/drugs/DB14459ApprovedWithdrawnThe influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus
Mixtures: Medical Provider Single Use EZ Flu Shot Afluria 2016-2017, Medical Provider Single Use EZ Flu Shot Fluvirin 2016-2017