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Cilastatin
go.drugbank.com/drugs/DB01597ApprovedInvestigationalCilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. … The first combination product containing both drugs was approved by the FDA in November of 1985 under the trade name Primaxin, marketed by Merck & Co.
Mixtures: Hovid Imipenem + Cilastatin for Injection 250mg/250mg, Imipenem and CilastatinCategories: imipenem and cilastatin, imipenem, cilastatin and relebactamArtemether
go.drugbank.com/drugs/DB06697ApprovedInvestigational</i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas. … Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy.
Mixtures: COARTEM® TABLETAS DISPERSABLES 20/120MGCategories: Artemisinin and derivatives, artemether and lumefantrineFencamfamin
go.drugbank.com/drugs/DB01463ApprovedIllicitWithdrawnIt is around half the potency of [dexamphetamine], and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose. … Fencamfamin is used for treating depressive day-time fatigue, lack of concentration and lethargy. It is especially useful in patients with chronic conditions due to its favourable safety profile.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsTechnetium Tc-99m disofenin
go.drugbank.com/drugs/DB09164ApprovedWithdrawnTechnetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with no known pharmacologic actions at the doses recommended. … It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary
Categories: Indicators and Reagents, Amino Acids, Peptides, and ProteinsAlcohol Withdrawal Associated Autonomic Hyperactivity
go.drugbank.com/conditions/DBCOND0052442Synonyms: [X]Mental and behavioral disorders due to use of alcohol: withdrawal state with delirium (disorder)EI-001
go.drugbank.com/drugs/DB17596InvestigationalSynonyms: Human monoclonal antibody based on an IgG1 lambda framework against human interferon gammaAtrial natriuretic peptide
go.drugbank.com/drugs/DB15591InvestigationalSynonyms: ANPCategories: Amino Acids, Peptides, and Proteins, Hormones, Hormone Substitutes, and Hormone AntagonistsQXL138AM
go.drugbank.com/drugs/DB18552InvestigationalQXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Synonyms: Masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2aLysine
go.drugbank.com/drugs/DB00123ApprovedInvestigationalNutraceuticalCollagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. … Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis.
Mixtures: Aminosyn II and Dextrose, Aminosyn II and DextroseCategories: arginine and lysine, Blood and Blood Forming OrgansHydroxyurea
go.drugbank.com/drugs/DB01005ApprovedInvestigationalHydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928. … need for therapeutic monitoring, and serious side effects of secondary cancer and birth defects.
Synonyms: N-Hydroxyurea, N-CarbamoylhydroxylamineCategories: Antineoplastic and Immunomodulating Agents