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Displaying results 2011 - 2020 of 10000 in total

Drug
Aniline
go.drugbank.com/drugs/DB06728
Investigational
Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. … Aniline is colorless, but it slowly oxidizes and resinifies in air, giving a red-brown tint to aged samples.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesSynonyms: Fentanyl impurity F, Trimethoprim specified impurity K
Drug
Gestodene
go.drugbank.com/drugs/DB06730
Investigational
Gestodene is a progestogen hormonal contraceptive.
Mixtures: FEMIANE®, FEMIANE®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
Drug
beta-Naphthoflavone
go.drugbank.com/drugs/DB06732
Experimental
β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). … It may be a chemopreventive agent.
Categories: Cytochrome P-450 CYP1A2 Inducers, Heterocyclic Compounds, 1-RingSynonyms: 3-phenyl-1H-naphtho(2,1-b)pyran-1-one, β-NF
Drug
Bafilomycin A1
go.drugbank.com/drugs/DB06733
Experimental
This is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis. … Bafilomycins are specific inhibitors of vacuolar-type H+-ATPase. (V-ATPase). The most commonly utilized bafilomycin is bafilomycin A1.
Drug
Zaltoprofen
go.drugbank.com/drugs/DB06737
Investigational
A non-steroidal anti-inflammatory drug approved for use in Japan in 1993.
Categories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDS
Drug
BW-A 58C
go.drugbank.com/drugs/DB06740
Experimental
BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy … metabolite in man in vivo and also in human liver microsomes, where this is catalysed primarily by a 54 kDa CYP2C9 form of cytochrome P450, P450hB20-27.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: 2-(4'-t-Butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone
Drug
Gavestinel
go.drugbank.com/drugs/DB06741
Experimental
Gavestinel displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites and is orally bioavailable and active in vivo.
Categories: Heterocyclic Compounds, 2-Ring
Drug
Ginsenoside Rb1
go.drugbank.com/drugs/DB06749
ExperimentalNutraceutical
Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. … Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng).
Synonyms: GRb 1, Gynosaponin C
Drug
Ginsenoside Rg1
go.drugbank.com/drugs/DB06750
ExperimentalNutraceutical
Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. … Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng).
Synonyms: Panaxoside A
Drug
Chymopapain
go.drugbank.com/drugs/DB06752
ApprovedWithdrawn
It is currently discontinued.[L2487] … [L2482]It is an extracellular plant cysteine proteinase similar to papain in specificity.[A32688] Chymopapain was developed by Chart Medcl and FDA approved on November 10, 1982.
Products: Chymodiactin Injection - 4 Nkat Units/2ml