Search

Displaying results 2011 - 2020 of 10000 in total
  1. Drug

    Albiglutide

    go.drugbank.com/drugs/DB09043
    ApprovedInvestigationalWithdrawn

    Albiglutide is a glucagon-like peptide-1 agonist (GLP-1) biologic drug indicated in the treatment of type 2 diabetes. It is marketed under the brands Eperzan and Tanzeum by GSK (GlaxoSmithKline). … It is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide was approved on April 15, 2014 by the FDA.

    Categories: Drugs Used in Diabetes, Glucagon-like peptide-1 (GLP-1) analogues
  2. Drug

    Trypan blue free acid

    go.drugbank.com/drugs/DB09158
    Approved

    Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. … This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    MCC

    go.drugbank.com/drugs/DB05282
    Investigational

    The product is a sterile biological composition in a sub-micron suspension. It is produced at the Bioniche manufacturing facility in Pointe-Claire, Quebec. … Mycobacterial Cell Wall-DNA Complex (MCC) is formulated from Mycobacterium phlei, a non-pathogenic strain of mycobacteria.

  4. Drug

    Tyloxapol

    go.drugbank.com/drugs/DB06439
    ApprovedInvestigational

    Tyloxapol is a non-ionic detergent often used as a surfactant.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    L-tartaric acid

    go.drugbank.com/drugs/DB09459
    Approved

    Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics … , and is a dihydroxyl derivative of succinic acid.

    Mixtures: E-Z-gas 2 Granules, SAL G.Synonyms: (+)-(R,R)-tartaric acid, (R,R)-Tartaric acid
  6. Drug

    Doxepin

    go.drugbank.com/drugs/DB01142
    ApprovedInvestigational

    [T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. … [T83] In a strict sense, doxepin is not a tricyclic antidepressant but it is commonly associated with the class since it shares a lot of properties with members of the drug family including [amitriptyline

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: PURDOX %5 KREM, 30 G, EXPAN® 50 MG
  7. Drug

    Omega-3 fatty acids

    go.drugbank.com/drugs/DB11133
    ApprovedInvestigationalNutraceutical

    The three types of omega-3 fatty acids involved in human physiology are α-linolenic acid (ALA) (found in plant oils), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) (both commonly found in … Omega-3 fatty acids play a critical role in metabolism and cellular function and they are available as daily supplements. On September 8, 2004, the U.S.

    Synonyms: n-3 PUFAs, n-3 fatty acidsMixtures: LIPOPLUS 20% ( EMULSION PARA PERFUSION IV.), LIPOPLUS 20% ( EMULSION PARA PERFUSION IV.)
  8. Drug

    Idebenone

    go.drugbank.com/drugs/DB09081
    ApprovedInvestigational

    LHON is a mitochondrially inherited degeneration of retinal ganglion cells, resulting in acute central vision loss. … Lack of improvement in cognitive function halted its production for these conditions, however it continues to be investigated for use in other conditions associated with mitochondrial damage.

    Mixtures: EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET, EVERON 90/5 MG FILM KAPLI TABLET ,100 TABLETCategories: Compounds used in a research, industrial, or household setting
  9. Pathway

    Tocainide Sodium Channel Cardiac Muscle Relaxation Action Pathway

    smpdb.ca/view/SMP0126519
    Drug action

    In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. … Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias.

    Drugs: Tocainide · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  10. Drug

    Avanafil

    go.drugbank.com/drugs/DB06237
    Approved

    Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. … In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a relatively

    Categories: Drugs Used in Erectile Dysfunction, Cytochrome P-450 SubstratesSynonyms: (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide