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Naphazoline
go.drugbank.com/drugs/DB06711ApprovedNaphazoline was first developed in 1942 as a nasal formulation for congestion[A176609]. … Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807].
Mixtures: SULFARHIN BURUN MERHEMI, 20 G, Opcon-ACategories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor AgonistsTofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. … Known adverse effects include nausea and headache as well as more serious immunologic and hematological adverse effects. Tofacitinib is marketed under the brand name Xeljanz by Pfizer.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: Tositin 10 mg Film Kaplı Tablet, 56 ADET, JANTY 5 MG FİLM KAPLI TABLET, 56 ADETConestat alfa
go.drugbank.com/drugs/DB09228ApprovedC1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. … Marketed as the product Ruconest (FDA), this drug is indicated for the treatment of acute attacks of hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency in adults.
Products: RUCONEST 2100 U IV ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 ADET, Berinert 2000 I.E. Pulver und Lösungsmittel zur Herstellung einer InjektionslösungAmsacrine
go.drugbank.com/drugs/DB00276ApprovedInvestigationalWithdrawnAminoacridine derivative that is a potent intercalating antineoplastic agent.
Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsSynonyms: m-AMSA, 4'-(9-Acridinylamino)methanesulfon-m-anisidideCangrelor
go.drugbank.com/drugs/DB06441ApprovedInvestigationalAn advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset … Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors.
Categories: Heterocyclic Compounds, 2-RingSynonyms: [dichloro-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acidEtonogestrel
go.drugbank.com/drugs/DB00294ApprovedInvestigationalEtonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. … [A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Mixtures: EXELRING ®, NUVARING®ANILLO VAGINALCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMagnesium gluconate
go.drugbank.com/drugs/DB13749ApprovedWithdrawnMagnesium gluconate is a magnesium salt of gluconate. It demonstrates the highest oral bioavailability of magnesium salts [L2608] and is used as a mineral supplement. … Magnesium is ubiquitous in the human body, and is naturally present in many foods, added to other food products, available as a dietary supplement and used as an ingredient in some medicines (such as antacids
Mixtures: K-med, Formula 9 TabSynonyms: Magnesium D-gluconate (1:2) dihydrate, Magnesium D-gluconate (1:2) hydrateSqualene
go.drugbank.com/drugs/DB11460ApprovedInvestigationalVet approvedWithdrawnIt is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation and provides skin protection. … Squalene is investigated as an adjunctive cancer therapy.
Mixtures: K-OMEGASQUA (Softgel)Synonyms: (E,E,E,E)-Squalene, (all-E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaeneProtirelin
go.drugbank.com/drugs/DB09421ApprovedIt is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary. … Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary
Synonyms: 5-oxo-L-prolyl-L-histidyl-L-prolinamide, L-pyroglutamyl-L-histidyl-L-prolineamideProducts: TRH FERRING 0,2 MG/ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADET, Relefact Trh Inj 0.2mg/mlNonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnNonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. … N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Nonoxynol 9, Nonoxynol-9