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Lecithin, soybean
go.drugbank.com/drugs/DB14161InvestigationalA complex mixture of phospholipids; glycolipids; and triglycerides; with substantial amounts of phosphatidylcholines; phosphatidylethanolamines; and phosphatidylinositols, which are sometimes loosely termed as 1,2-diacyl-3-phosphocholine...
Mixtures: GNC PP AA FormulaNeutral amino acid transporter B(0)
go.drugbank.com/bio_entities/BE0000236TargetTransporterHumansMediates D-serine release from the retinal glia potentially affecting NMDA receptor function in retinal neurons.
Synonyms: Baboon M7 virus receptor, RD114/simian type D retrovirus receptorDeoxyhypusine hydroxylase
go.drugbank.com/bio_entities/BE0018877TargetHumansCatalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-tran...
Synonyms: HEAT-like repeat-containing protein 1CD320 antigen
go.drugbank.com/bio_entities/BE0019797TransporterHumansReceptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389). Plays an important role in cobalamin uptake (PubMed:18779389, PubMed:20524213).
Synonyms: Transcobalamin receptorVolume-regulated anion channel subunit LRRC8A
go.drugbank.com/bio_entities/BE0016599TargetHumansEssential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24725410, PubM...
Synonyms: Leucine-rich repeat-containing protein 8ASteroidogenic factor 1
go.drugbank.com/bio_entities/BE0003359TargetHumansTranscriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues (PubMed:27378692). Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B a...
Synonyms: Steroid hormone receptor Ad4BP, Nuclear receptor subfamily 5 group A member 1Janus (JAK) kinases
go.drugbank.com/bio_entities/BE0027976TargetHumansThe heterodimeric cytokine receptor complexes are composed of (1) a TYK2-associated receptor chain (IFNAR1, IL12RB1, IL10RB or IL13RA1), and (2) a second receptor chain associated either with JAK1 or JAK2 … Involved in the oncostatin-M-mediated signaling pathway through both type I OSM receptor complex (heterodimers composed of LIFR and IL6ST) and type II OSM receptor complex (heterodimers composed of OSMR
Polypeptides: Non-receptor tyrosine-protein kinase TYK2Function: acetylcholine receptor bindingTransforming growth factor beta activator LRRC32
go.drugbank.com/bio_entities/BE0014554TargetHumansKey regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19651619, PubMed:19750484, PubMed:22278742). As...
Synonyms: Leucine-rich repeat-containing protein 32Function: receptor ligand inhibitor activityAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigational[A18262] Use of non-stimulant medications such as atomoxetine is therefore thought to offer a clinical advantage over the use of traditional medications for the management of ADHD. … positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate (NMDA) receptor
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigational[A177577, A177580] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors