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Omeprazole
go.drugbank.com/drugs/DB00338ApprovedInvestigationalVet approvedOriginally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders.
Mixtures: ORAZOLE ® 10 MG CAPSULA, OMEPRAZOL 20 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedPharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label]. … A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609].
Categories: Cytochrome P-450 CYP2A6 Inducers, Cytochrome P-450 SubstratesProducts: N/A, GESTAGENO® 200 MG CÁPSULAS DE GELATINA BLANDACisplatin
go.drugbank.com/drugs/DB00515ApprovedInvestigationalCisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung
Categories: OCT2 Substrates with a Narrow Therapeutic Index, Compounds used in a research, industrial, or household settingProducts: BLASTOLEM RU 10 MG SOLUCION INYECTABLE, BLASTOLEM RU SOLUCION INYECTABLE 50 MGTretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceuticalTretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). … [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism.
Synonyms: Tretin M, Vitamin A acidInternational brands: Stieva-AIron sucrose
go.drugbank.com/drugs/DB09146ApprovedInvestigational(hemodialysis or peritoneal) and those who do not require dialysis. … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis
Mixtures: Myferon 150 ForteProducts: HIERRO SACARATO EQUIVALENTE A HIERRO ELEMENTAL 100 MG/ 5ML., Myferon 150Sulpiride
go.drugbank.com/drugs/DB00391ApprovedWithdrawn[A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses.
Mixtures: NEUPAX DUO-SCategories: Dopamine D2 Receptor AntagonistsTemozolomide
go.drugbank.com/drugs/DB00853ApprovedInvestigational[L32033] Temozolomide was granted FDA approval on August 11, 1999, as an oral capsule and subsequently on February 27, 2009, as an intravenous injection. … [A229848, A229858, L32033] Temozolomide is an imidazotetrazine prodrug that is stable at acidic pH but undergoes spontaneous nonenzymatic hydrolysis at neutral or slightly basic pH; these properties allow
Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide, 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-oneSugammadex
go.drugbank.com/drugs/DB06206ApprovedInvestigationalSugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015. … Sugammadex provides a new treatment option to reverse the effects of those medications and possibly help patients recover sooner post-surgery.
Categories: Compounds used in a research, industrial, or household settingProducts: SUGAMMADEX DR. REDDY'S, Sugagelan 100 mg/ml-InjektionslösungCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalIt is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. … Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of depression.
Mixtures: Sentralopram AM-10Categories: Monoamine Oxidase A Substrates, Cytochrome P-450 SubstratesNateglinide
go.drugbank.com/drugs/DB00731ApprovedDue to their mechanism of action, meglitinides may cause hypoglycemia although the risk is thought to be lower than that of sulfonylureas since their action is dependent on the presence of glucose. … Nateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). The major metabolites possess less activity than the parent compound.
Mixtures: NATMET 120/850 MG TEDAVI PAKETI, 90+90 ADET, NATPLUS 180/850 MG TEDAVI PAKETI, 90+90 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates