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Trimipramine
go.drugbank.com/drugs/DB00726ApprovedInvestigationalTricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: TRIMIPRAMIN AL 25MG TABL, TRIMIPRAMIN AL 100MG TABLPipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnHowever, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. … Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: PIPORTIL ® L-4SOLUCION INYECTABLE AL 2.5% (100 MG).Bezafibrate
go.drugbank.com/drugs/DB01393ApprovedInvestigationalAntilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acidCat dander extract
go.drugbank.com/drugs/DB13904ApprovedIt is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats. … An allergic reaction to cats is induced by the presence of antigen-specific IgE antibodies that are bound to specific receptors on mast cells and basophils.
Products: Standardized Cat Hair ApNitrendipine
go.drugbank.com/drugs/DB01054ApprovedWithdrawnNitrendipine is a calcium channel blocker with marked vasodilator action. … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: NITRENDIPIN AL 10, NITRENDIPIN AL 20Zonisamide
go.drugbank.com/drugs/DB00909ApprovedInvestigationalZonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures. … [L42530,L42535] Zonisamide represents an alternative for patients that remain refractory to established antiepileptic drugs. In 1989, it was approved for commercial use in Japan.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Compounds used in a research, industrial, or household settingProducts: ZONISAMID AL 25 MG HKP, ZONISAMID AL 50 MG HKPPoa annua pollen
go.drugbank.com/drugs/DB10353ApprovedPoa annua pollen is the pollen of the Poa annua plant. Poa annua pollen is mainly used in allergenic testing.
Products: Center-AL - Poa Annua PollenJuglans californica pollen
go.drugbank.com/drugs/DB10397ApprovedJuglans californica pollen is the pollen of the Juglans californica plant. Juglans californica pollen is mainly used in allergenic testing.
Products: Center-AL - Juglans Californica PollenLansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigationalLansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. … [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)
Mixtures: Aa-lansoprazole-amoxicillin-clarithromycinCategories: P-glycoprotein inhibitors, P-glycoprotein substratesAprepitant
go.drugbank.com/drugs/DB00673ApprovedInvestigationalAprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. … Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InducersProducts: APREPITANT AL 80MG HKP, APREPITANT AL 125MG HKP